CAS: 6531-35-7; 2,3-Dimethylanthracene-9,10-Dione

上下游产品

2,3-dimethyl-9(10H)-anthracenone 2-benzoyl-4,5-dimethylbenzoic acid 2-(3,4-dimethylbenzoyl)benzoic acid 6,7-dimethyl-9,10-dioxo-9,10-dihydro-anthracene-1-carboxylic acid 2,3,9,10-Tetramethyl-anthracen 2,3-dimethyl-9,10-diphenyl-9,10-dihydro-anthracene-9,10-diol 2,3-dimethylanthracene 1-amino-2,3-dimethyl-9,10-anthraquinone

📜2,3-Dimethyl-1,4,4A,9A-Tetrahydro-9,10-Anthracenedione置于氢氧化钾,Air体系中,用 乙醇 作为反应溶剂,以36.7 G的收率获得产物2,3-二甲基蒽醌
参考文献:(E)-(2-蒽基)乙烯的旋转异构化.一个考虑为什么thes-Cisrotamers在激发态比thes-Transrotamers更稳定而在基态更不稳定
标题:(E)-(2-蒽基)乙烯的旋转异构化.一个考虑为什么thes-Cisrotamers在激发态比thes-Transrotamers更稳定而在基态更不稳定
摘要:(E)-1-(2-蒽基)-2-苯基乙烯 (E-2Ape) 和 (E)-1-(2-蒽基)-3,3-二甲基的 S-Cis 和 S-Trans 旋转异构体之间的旋转异构现象-1-丁烯 (E-2Adb) 通过与模型化合物的吸收,发射和瞬态吸收光谱进行比较来研究.s-反式异构体在基态下比s-顺式旋转异构体更稳定;然而,在激发态(最低的单线态和三线态激发态),S-顺式异构体比s-反式旋转异构体更稳定.在三重激发态下,E-2Ape 和 E-2Adb 的活化能分别为 30 和 18 Kj Mol-1,观测到 S-Trans-> S-Cis 单向旋转异构化.
DOI:10.1246/bcsj.72.1837

专利信息

专利号:US-4021457-A
优先权日:1975-11-18
标 题 :Intermediates for polycyclic quinonoid antibiotics
发明人：KENDE ANDREW S; MILLS JOHN E; TSAY YUH-GENG
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of certain analogs of (+)-7-deoxydaunomycinone which includes the provision of novel tri- and tetracyclic quinone intermediates. The products of the synthetic route provided herein may be converted into compounds of known anti-neoplastic activity.