CAS: 628-41-1; Cyclohexa-1,4-Diene

该化合物是一种循环碳氢化合物,其分子式为C6H8,其特点是位于环氧环1和4位置上的两个双环,该化合物在室内温度下是一种无色液体,有独特的气味,因其反应作用而闻名,特别是在Diels-Alder反应中,由于存在同源双环结合,这增强了其参与电益添加反应的能力.该化合物与其饱和对应方(环己烷)相比相对不稳定,并在某些条件下可发生聚合或氧化.1,4-Cyclohexadiene在有机溶剂中溶解,但在水中溶解性有限.该化合物用于有机合成和作为各种化学品生产的中间体.在处理该物质时,必须采取安全防范措施,因为它可能是易燃的,如果吸入或摄取,可能会对健康造成危害.应当遵循适当的储存和处理程序来减轻这些风险.

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CAS号2235-12-3 1,3,5-已三烯 | CAS号1165952-91-9 cyclohexa-1,3-diene

合成工艺路线路线简述

    📜(4Z,7Z,10Z)-Tetradeca-1,4,7,10,13-Pentaene置于grubbs Catalyst First Generation体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 1,4-环己二烯
    参考文献:Guiard; Santelli; Parrain,Synlett,2001,# 4,P. 553-556
    标题:Guiard; Santelli; Parrain,Synlett,2001,# 4,P. 553-556

    海关参考信息

    专利信息


    专利号:US-11236029-B2
    优先权日:2019-05-17
    标题 :Synthesis of a triangulene ring system and derivatives thereof
    发明人:JOHNSON RICHARD PETER; HOLT CARTER J
    权利人:THE UNIV OF NEW HAMPSHIRE; UNIV NEW HAMPSHIRE
    摘要:A three step synthesis of the 8,12-dihydro-4H-dibenzo[cd,mn]pyren-3a 2 -ylium cation (triangulenium cation) is effected by cascade cyclization of a tetra-benzyl alcohol precursor in triflic acid solution. This cation is easily observed by NMR and optical spectroscopy. Quenching of the cation into basic solutions or by hydride transfer from triethylsilane provides access to stable dihydro and tetrahydro[3]triangulenes. This route makes several [3]triangulene precursors more readily available for development of new applications in the field of molecular electronics.

    专利号:US-7973171-B2
    优先权日:2005-06-13
    标题:Process for synthesis of dialkoxyorganoboranes
    发明人:BURKHARDT ELIZABETH; ATKINS WILLIAM
    权利人:BURKHARDT ELIZABETH; ATKINS WILLIAM
    摘要:The invention relates to a process for the synthesis of dialkoxyorganoboranes, in particular to a process for the synthesis of dialkoxyorganoboranes by an ester exchange reaction. Moreover, the invention relates to a process for the synthesis of organo-oxazaborolidine catalysts (organo-CBS) and of trialkylboroxins. Furthermore, the invention relates to methods of using dialkoxyorganoboranes for the preparation of organo-CBS catalysts and in Suzuki-type coupling reactions.

    专利号:US-5442065-A
    优先权日:1993-09-09
    标 题:Synthesis of tetrahydroquinoline enediyne core analogs of dynemicin
    发明人:MAGNUS PHILIP D; ILIADIS THEODORE; EISENBEIS SHANE A; FAIRHURST ROBIN A
    权利人:UNIV TEXAS
    摘要:A process is described for the preparation of the core azobicyclo[7.3.1]tridecaenediyne moiety of the antitumor antibiotic dynemicin. The synthesis allows efficient production of the enediyne as a stable, compound in good yield from the adamantyl N-protected azabicyclo[7.3.1]tridecadiyne. The adamantyl protecting group is employed in the starting material, N-adamantyl dihydroquinoline or N-adamantyl 6-methoxy quinoline. Also disclosed are process for the synthesis of 3-hydroxy-6-methoxyquinoline and several N-substituted derivatives of azobicyclo[7.3.1]tridecaenediyne. Solid tumor and leukemia assays were performed on the analogs of dynemicin. The results suggest a method that these compounds will useful in treating certain types of leukemias and solid tumors. The disclosed synthesis provides a route to new dynemicin intermediates and analogs which will allow development of second and third generation dynemicins.

    专利号:WO-2023102600-A1
    优先权日:2021-12-06
    标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom
    发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI
    权利人:NEWSOUTH INNOVATIONS PTY LTD
    摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.

    专利号:US-6818777-B2
    优先权日:2000-12-07
    标 题:Intermediates for synthesis of vinblastine compound and method for synthesizing the intermediate
    发明人:FUKUYAMA TOHRU; TOKUYAMA HIDETOSHI
    权利人:JAPAN SCIENCE & TECH AGENCY
    摘要:Intermediates A, which are important in the whole synthesis of vindoline; and a method of synthesizing intermediates respectively represented by the general formulae B and C. By the method, the target intermediates are effectively synthesized with satisfactory reproducibility. This synthesis method is especially suitable for mass production. General formula A General formula B General formula C.

    专利号:US-7138526-B1
    优先权日:1999-06-15
    标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
    发明人:HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
    权利人:AVENTIS PHARMA INC
    摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

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    合成参考文献


    参考文献:10.1021/ja205816d
    摘要:Summerscales OT, Fettinger JC, Power PP. C-H activation of cycloalkenes by dimetallynes (M = Ge, Sn) under ambient conditions. J Am Chem Soc. 2011 Aug 10;133(31):11960–3. doi: 10.1021/ja205816d.
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