CAS: 475060-21-0; N-(5-Fluoro-4-Methylpyridin-2-yl)Acetamide

该化合物是一种氟虫胺衍生物,可能用于制药和农用化学研究,其结构以环上的氟替代组和甲基组为主,增强了分子相互作用的回活动性和约束性.乙酰胺进一步有助于其作为有机合成中间体的多功能性.该化合物在标准条件下具有稳定性,适合进一步功能化,因此具有价值,有助于生物活性分子的开发.高纯度可用于确保研究和工业应用的一致性.建议适当处理和储存以保持其完整性.

英文名称N-(5-Fluoro-4-Methylpyridin-2-yl)Acetamide
中文名称N-(5-氟-4-甲基吡啶-2-基)乙酰胺
IUPAC名称N-(5-fluoro-4-methylpyridin-2-yl)acetamide
其它别名2-Acetamido-5-Fluoro-4-Methylpyridine; 2-Acetamido-5-Fluoro-4-Picoline; N-(5-Fluoro-4-Methylpyridin-2-yl)Acetamide; N-(5-Fluoro-4-Methyl-2-Pyridinyl)-Acetamide; Acetamide, N-(5-Fluoro-4-Methyl-2-Pyridinyl)-
CAS编号475060-21-0
MFCD编号:MFCD05662404
分子式:C8H9FN2O分子量:168.17
产品CID: 1468568
产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物

相似结构搜索
InChIKey: FNHPTZIEXVBRFX-UHFFFAOYSA-N
InChI=1S/C8H9FN2O/c1-5-3-8(11-6(2)12)10-4-7(5)9/h3-4H,1-2H3,(H,10,11,12)
计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数1.0

相似化合物

100304-88-9 1101061-01-1 2738981-03-6

MSDS等安全信息

上下游产品

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合成工艺路线路线简述

📜2-氨基-4-甲基-5-硝基吡啶置于palladium On Activated Charcoal Tetrafluoroboric Acid,氢气,Sodium Nitrite体系中,用甲苯作为反应溶剂,化学反应生成 N-(5-氟-4-甲基吡啶-2-基)乙酰胺
参考文献:Mexab-Oprm Specific Efflux Pump Inhibitors In Pseudomonas Aeruginosa. Part 4: Addressing The Problem Of Poor Stability Due To Photoisomerization Of An Acrylic Acid Moiety
标题:Mexab-Oprm Specific Efflux Pump Inhibitors In Pseudomonas Aeruginosa. Part 4: Addressing The Problem Of Poor Stability Due To Photoisomerization Of An Acrylic Acid Moiety
摘要:Exchange Of The Ethylene Tether In A Series Of Pyridopyrimidine-Based Mexab-Oprm Specific Efflux Pump Inhibitors To An Amide Bond Stabilized The Olefin Of The Acrylic Acid Moiety,Preventing Facile Photoisomerization To The Z-Isomer. Furthermore,The Activity Was Drastically Improved In The Amide Tether Variants,Providing Extremely Potent Acrylic Acid And Vinyl Tetrazole Analogues. (C) 2004 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2004.03.007