CAS: 3330-05-0; α-Ethyl-N,N-Dimethylbenzenemethanamine

上下游产品

2-(N,N-dimethylamino)-2-phenylacetonitrile ethylmagnesium bromide ethyl-(1-phenyl-propenyl)-ether dimethyl amineTrimethyl-1-phenyl-propyl-ammonium methiodide 1-phenyl-1-(4-methylphenylthio)propane

📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid 以 乙醇 作为反应溶剂,以87%的收率获得产物达泊西汀杂质12
参考文献:通过胺-硼烷络合物金属化苄胺
标题:通过胺-硼烷络合物金属化苄胺
摘要:的硼烷配合物的形成ñ,ñ-Dimethylbenzylamine,ñ,ñ-二甲基(1-萘基)甲胺,ñ,ñ-二甲基(2-萘基)甲胺,ñ-Methyltetrahydroisoquinoline和ñ-Methylisoindoline有助于使用丁基锂这些系统的区域选择性金属化反应生成中间体苄基阴离子,该阴离子可与一系列亲电试剂反应,从而以高收率获得产物.
DOI:10.1016/s0040-4020(98)00783-2

专利信息

专利号:WO-2012001571-A1
优先权日:2010-07-02
标题 :New process for the synthesis of tapentadol and intermediates thereof

专利号:EP-2588429-A1
优先权日:2010-07-02
标 题:New process for the synthesis of tapentadol and intermediates thereof