CAS: 32511-34-5; (2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]Heptan-2-Amine

相似化合物

32511-35-6 1822315-84-3 24629-78-5

上下游产品

CAS号2792-42-9 樟脑肟 | CAS号464-49-3 D(+)-樟脑 | CAS号540-69-2 甲酸铵 | CAS号77287-34-4 甲亚胺酸 | CAS号464-43-7 右莰醇 | CAS号37850-13-8 (-)-(1R,4R)-Cam... | CAS号76-22-2 (±)-樟脑(合成) | CAS号6535-09-7 (-)-2exo-bromo-... | CAS号64-17-5 乙醇 | CAS号71-41-0 正戊醇 | CAS号464-17-5 1,7,7-三甲雙環[2.2.... | CAS号464-49-3 D(+)-樟脑 | CAS号24629-79-6 N-(4,7,7-trimet... | CAS号73657-24-6 (1R,2s)-(+)-冰片胺盐酸盐 | CAS号7785-53-7 (+)-α-松油醇 | CAS号465-31-6 camphene hydrate | CAS号79-92-5 莰烯

📜(+)-冰片置于十二羰基三钌,4,5-二-(二-异丙基膦基甲基)吖啶,氨体系中,用 2-甲基-2-丁醇 用作溶剂,化学反应 21.0H,反应生成(R)-(+)-莰胺
参考文献:使用氨直接胺化生物酒精
标题:使用氨直接胺化生物酒精
摘要:略有适应的催化剂体系已成功应用于伯醇和仲醇的直接胺化.而且,已经显示出对二醇的适用性,从而对伯二胺具有高选择性.发现ru / P比以及所用氨的量在该系统中非常重要,特别是对于较高的底物负载.将该催化剂以较大的批量规模使用,以将异甘露聚糖转化为相应的二胺.另外,表明该催化剂在至少六个连续运行中是稳定的.没有观测到明显的活性和选择性损失.
Doi:10.1002/cctc.201300407

专利信息

专利号:US-7323575-B2
优先权日:2003-04-09
标题:Process for the synthesis of (2S)-indoline-2-carboxylic acid
发明人：SOUVIE JEAN-CLAUDE; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): n nApplication in the synthesis of perindopril and its pharmaceutically acceptable salts.

专利号:US-7196204-B2
优先权日:2003-04-09
标 题:Method for the synthesis of s-indoline-2-carboxylic acid and application thereof in the synthesis of perindopril

专利号:US-2006183919-A1
优先权日:2003-04-09
标 题 :Novel method for the synthesis of s-indoline-2- carboxylic acid and application thereof in the synthesis of perindopril

专利号:CA-2521877-C
优先权日:2003-04-09
标题 :Novel method for the synthesis of s-indoline-2-carboxylic acid and application thereof in the synthesis of perindopril

专利号:CN-1768019-A
优先权日:2003-04-09
标 题 :method for synthesis of (2s)-indoline-2-carboxylic acid and use in the synthesis of perindopril

专利号:DE-60303904-T2
优先权日:2003-04-09
标题 :Process for the synthesis of (2S) -indoline-2-carboxylic acid, and use in the synthesis of perindopril