CAS: 25379-88-8; Methyl 2-(3,4-Dihydroxyphenyl)Acetate

上下游产品

CAS号67-56-1 甲醇 | CAS号775-01-9 DL-3,4-二羟基扁桃酸 | CAS号14199-15-6 对羟基苯乙酸甲酯 | CAS号29413-65-8 methyl 2-(3,4-d... | CAS号7664-93-9 硫酸 | CAS号102-32-9 3,4-二羟基苯乙酸 | CAS号156-38-7 对羟基苯乙酸 | CAS号326-59-0 苯并[1,3]二氧代l-5-乙酸甲酯 | CAS号93-40-3 3,4-二甲氧基苯乙酸 | CAS号2861-28-1 2-(苯并[d][1,3]二氧... | CAS号7417-21-2 2-(3,4-二甲氧基苯基)乙醇 | CAS号6845-81-4 苯并[1,3]二氧代-5-乙酰氯 | CAS号13023-73-9 2-(3,4-dihydrox... | CAS号10597-60-1 3,4-二羟基苯乙醇 | CAS号15964-79-1 3,4-二甲氧基苯乙酸甲酯 | CAS号1129-53-9 3,4-二羟基苯乙酰胺 | CAS号5707-55-1 Dopal

4-羟基苯乙酸甲酯置于sodium Percarbonate,三乙胺,Magnesium Chloride体系中,用 四氢呋喃,水,乙腈 用作溶剂,化学反应 2.5H,反应生成3,4-二羟基苯乙酸甲酯
参考文献:羟基酪醇及其中间体的合成工艺
标题:羟基酪醇及其中间体的合成工艺
摘要:本发明公开了一种羟基酪醇及其中间体的合成工艺,属于合成技术领域.羟基酪醇中间体的合成工艺:2‑(3‑甲酰基‑4‑羟基苯基)乙酸酯经氧化反应得到羟基酪醇中间体.羟基酪醇的合成工艺包括如下步骤:A.对羟基苯乙酸经催化酯化反应制备得到对羟基苯乙酸酯;B.对羟基苯乙酸酯经甲酰化反应制备得到2‑(3‑甲酰基‑4‑羟基苯基)乙酸酯;C.2‑(3‑甲酰基‑4‑羟基苯基)乙酸酯经氧化反应制备得到羟基酪醇中间体;D.羟基酪醇中间体经还原反应制备得到羟基酪醇.本发明的制备方法起始物料价格便宜,各步反应条件温和,收率高,适合工业化生产,可有效解决现有制备羟基酪醇的方法成本较高,不适于工业化大规模生产的问题.

专利信息

专利号:US-7022691-B2
优先权日:2002-04-04
标题 :Inhibitors of serine and metallo-β-lactamases
发明人：BUYNAK JOHN D; CHEN HANSONG
权利人:BUYNAK JOHN D; CHEN HANSONG
摘要:Compounds of formula (I): n nwherein R 1 , R 2 , R 3 , R 4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting simultaneously serine and metallo-β-lactamase enzymes, for enhancing the activity of β-lactam antibiotics, and for treating β-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and novel intermediates useful for the synthesis of compounds of formula I.

专利号:US-7125986-B2
优先权日:1997-12-29
标题:Penicillanic acid derivative compounds and methods of making
发明人：BUYNAK JOHN D; RAO AKIREDDY SRINIVASA; DOPPALAPUDI VENKATA RAMANA
权利人:UNIV SOUTHERN METHODIST
摘要:Compounds of formula I: n nwherein R 1 , R 2 , R 3 , R 4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting β-lactamase enzymes, for enhancing the activity of β-lactam antibiotics, and for treating β-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and novel intermediates useful for the synthesis of compounds of formula I.

专利号:CN-114195640-B
优先权日:2021-12-27
标 题 :Synthesis process of hydroxytyrosol and its intermediates