CAS: 1949-88-8; (2R,3S,4S,5S)-2,3,4,5,6-Pentahydroxyhexanal

化学文摘社编号1949-88-8,是有助于科学文献中对这一化合物进行分类和研究的独特识别资料.此外,L-Altrose可以参与淋巴素反应,有助于形成对细胞功能至关重要的甘代石素和甘基脂.

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相似化合物

10030-80-5 50-99-7 2595-98-4

上下游产品

mannitol para-xylene water D-sorbitol5-hydroxymethyl-2-furfuraldehyde glycolic Acid LACTIC ACID mannitol

合成工艺路线路线简述

    📜在 Palladium Dihydroxide 氢气体系中,用 四氢呋喃,水 用作溶剂,化学反应生成L-阿卓糖
    参考文献:从常见的手性结构单元到醛糖己糖的新的聚合路线.
    标题:从常见的手性结构单元到醛糖己糖的新的聚合路线.
    摘要:[文本中的反应]从常见的环己酸手性结构单元开始,开发了一种非对映控制的途径来合成8个醛己糖.
    Doi:10.1021/ol015733I

    海关参考信息

    专利信息


    专利号:US-7344863-B2
    优先权日:1998-03-13
    标题:Methods for producing polypeptides through enhanced synthesis of encoding nucleic acid molecules
    发明人:LI WU-BO; JESSEE JOEL A; SCHUSTER DAVID; XIA JIULIN; GEBEYEHU GULILAT
    权利人:INVITROGEN CORP
    摘要:The present invention is directed to compositions and methods for enhancing synthesis of nucleic acid molecules, particularly GC-rich nucleic acid molecules. Specifically, the invention provides compositions comprising one or more nitrogen-containing organic compounds having a formula selected from the group consisting of formula I and formula II (or salts or derivatives thereof), preferably 4-methylmorpholine N-oxide or betaine (carboxymethyltrimethylammonium), and further comprising one or more compounds selected from the group consisting of proline and an N-alkylimidazole compound, and more preferably proline, 1-methylimidazole or 4-methylimidazole. The invention further relates to methods for enhanced, high-fidelity synthesis of nucleic acid molecules, including via amplification (particularly PCR), reverse transcription, and sequencing methods. The invention also relates to nucleic acid molecules synthesized by these methods, to fragments or derivatives thereof, and to vectors and host cells comprising such nucleic acid molecules, fragments, or derivatives. The invention also relates to kits for synthesizing, amplifying, reverse transcribing or sequencing nucleic acid molecules comprising one or more of the compositions of the invention.

    专利号:US-9034844-B2
    优先权日:2009-04-06
    标 题 :6′-sialyllactose salts and process for their synthesis and for the synthesis of other alpha-sialyloligosaccharides
    发明人:TAMERLANI GIANCARLO; LOMBARDI ILARIA; BARTALUCCI DEBORA; DANESI ANDREA; SALSINI LIANA; MANONI MARCO; CIPOLLETTI GIOVANNI
    权利人:TAMERLANI GIANCARLO; LOMBARDI ILARIA; BARTALUCCI DEBORA; DANESI ANDREA; SALSINI LIANA; MANONI MARCO; CIPOLLETTI GIOVANNI; INALCO SPA
    摘要:The present invention relates to a process of synthesis of α-sialyl oligosaccharides and in particular of 6′-sialyllactose and its salts comprising a step of coupling by Koenigs-Knorr reaction under conditions that allow its use on an industrial scale.

    专利号:US-2024024489-A1
    优先权日:2020-11-20
    标 题:Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
    发明人:MULARD LAURENCE; DHARA DEBASHIS; PFISTER HELENE; PAOLETTI JULIE; PHALIPON ARMELLE; GUERREIRO-INVERNO CATHERINE
    权利人:PASTEUR INSTITUT
    摘要:The present invention provides zwitterionic oligosaccharides, in particular fragments of the surface polysaccharides from Shigella sonnei and Shigella sonnei conjugates comprising them. The present invention also provides protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof, the disaccharide repeating unit of Shigella sonnei being: (I)

    专利号:US-7429658-B2
    优先权日:2003-09-11
    标题 :Synthesis of protected pyrrolobenzodiazepines
    发明人:HOWARD PHILIP; MASTERSON LUKE
    权利人:SPIROGEN LTD
    摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):

    专利号:US-10973847-B2
    优先权日:2017-06-30
    标题 :Core-to-surface polymerization for the synthesis of star polymers and uses thereof
    发明人:JOHNSON JEREMIAH A; GOLDER MATTHEW R
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:Disclosed are methods, compositions, reagents, systems, and kits to prepare star polymers, as well as compositions and uses thereof. Various embodiments show that synthesis of these polymers contain low metal concentration to provide polymers for diverse biomedical applications including in vivo applications.

    专利号:US-8183355-B2
    优先权日:2006-04-28
    标题 :Method for the synthesis of oligonucleotide derivatives
    发明人:MORVAN FRANCOIS; MEYER ALBERT; VASSEUR JEAN-JACQUES; VIDAL SEBASTIEN; CLOAREC JEAN-PIERRE; CHEVOLOT YANN; SOUTEYRAND ELIANE
    权利人:MORVAN FRANCOIS; MEYER ALBERT; VASSEUR JEAN-JACQUES; VIDAL SEBASTIEN; CLOAREC JEAN-PIERRE; CHEVOLOT YANN; SOUTEYRAND ELIANE; CENTRE NAT RECH SCIENT
    摘要:Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted on the oligonucleotide with the help of a “click chemistryâ€? reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide, or between an alkyne function on the molecule of interest and an azide function on the oligonucleotide. n Intermediate molecules, notably alkyne functionalized oligonucleotides, grafted oligonucleotides, azide functionalized oligonucleotides, oligonucleotide micro arrays containing them and the use of those grafted oligonucleotides for biological investigation and for cell targeting.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Two-Step Synthesis Of Per-O-Acetylfuranoses: Optimization And Rationalization
    作者:Rémy Dureau,Laurent Legentil,Richard Daniellou,Vincent Ferrières |发布日期:2012.2.3
    摘要:A Simple Two-Step Procedure Yielding Peracetylated Furanoses Directly From Free Aldoses Was Implemented. Key Steps Of The Method Are (I) Highly Selective Formation Of Per-O-(Tert-Butyldimethylsilyl)Furanoses And (II) Their Clean Conversion Into Acetyl Ones Without Isomerization. This Approach Was Easily Applied To Galactose And Structurally Related Carbohydrates Such As Arabinose, Fucose, Methyl Galacturonate

    合成参考文献


    参考文献:10.1007/s00253-018-9018-1
    摘要:Vergne-Vaxelaire C, Mariage A, Petit JL, Fossey-Jouenne A, Guérard-Hélaine C, Darii E, Debard A, Nepert S, Pellouin V, Lemaire M, Zaparucha A, Salanoubat M, de Berardinis V. Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars. Appl Microbiol Biotechnol. 2018 Jul;102(13):5569–83. doi: 10.1007/s00253-018-9018-1.
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