📜2-[2-(4-Acetoxyphenyl)Diazenyl]Benzoic Acid置于phosphate Buffer体系中,化学反应生成2-(4-羟基苯唑)苯甲酸 参考文献:Vetter; Bayer; Wilchek,Journal Of The American Chemical Society,1994,Vol. 116,# 20,P. 9369-9370 标题:Vetter; Bayer; Wilchek,Journal Of The American Chemical Society,1994,Vol. 116,# 20,P. 9369-9370
专利号:US-12053529-B2 优先权日:2018-08-01 标题:Amino-reactive positively charged ATRP initiators that maintain their positive charge during synthesis of biomacro-initiators 发明人:RUSSELL ALAN J; MURATA HIRONOBU 权利人:UNIV CARNEGIE MELLON 摘要:Provided herein are materials and methods that include utilizing atom transfer radical polymerization (ATRP) initiator molecules that maintain a positive charge during biomacro-initiator synthesis.
专利号:US-2006286379-A1 优先权日:2002-08-13 标题 :Magnetic nanoparticle supports 发明人:GAO YONG 权利人:GAO YONG 摘要:Coated magnetic nanoparticles and their compositions used for labeling, detecting, sorting, and isolating biological, organic and inorganic molecules, and for medical therapies, and as a platform for organic, biological and physical transformations. An oxidation approach for fabricating iron oxide nanoparticles, methods for the synthesis of magnetic compositions comprising a magnetic core associated with a functional molecule or molecular complexes, and methods for the synthesis of water-soluble magnetic particles/compositions.
专利号:WO-2017197499-A1 优先权日:2016-04-25 标 题 :Stabilized hemoglobin-avidin assembly and method of preparation 发明人:KLUGER RONALD HENRY; SINGH SERENA 权利人:GOVERNING COUNCIL UNIV TORONTO 摘要:The disclosure concerns a hemoglobin based oxygen carrier (HBOC) comprising avidin or streptavidin and a hemoglobin conjugate preferably comprising a conjugate of hemoglobin and biotin where the conjugate is associated with avidin. The HBOC is capable of binding oxygen and releasing same in circulation in animals or humans. The design of the HBOC is intended so that it would not be vasoactive in vivo . The disclosure also concerns a method of synthesis and a method of use, or the use, of the HBOC for providing oxygen transport in the circulatory system of a human or animal.
专利号:WO-2019028168-A1 优先权日:2017-08-01 标 题:SOLID PHASE SYNTHESIS OF PROTEIN-POLYMER CONJUGATES ON IMMOBILIZATION MEDIA
专利号:WO-2020028715-A1 优先权日:2018-08-01 标题 :Amino-reactive positively charged atrp initiators that maintain their positive charge during synthesis of biomacro-initiators
专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.