CAS: 145736-65-8; 2-(3,4-Dimethoxyphenyl)Ethanethioamide

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CAS号93-17-4 3,4-二甲氧基苯乙腈 | CAS号93-17-4 3,4-二甲氧基苯乙腈

📜3,4-二甲氧基苯乙腈置于盐酸,硫代乙酰胺体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 2.0H,反应生成3,4-二甲氧基苯基硫代乙酰胺
参考文献:Novel Thiazole Derivatives As Inhibitors Of Superoxide Production By Human Neutrophils: Synthesis And Structure-Activity Relationships
标题:Novel Thiazole Derivatives As Inhibitors Of Superoxide Production By Human Neutrophils: Synthesis And Structure-Activity Relationships
摘要:Neutrophils Have An Important Role In The Self-Defense Systems Of Organisms Through The Production Of Superoxide. On The Other Hand,It Has Been Proposed That Abnormal Amounts Of Superoxide Produced By Neutrophils Are A Serious Factor In Tissue Injury. A Series Of Novel Thiazole Derivatives Was Prepared And Evaluated Inhibitory Effect On Superoxide Production By Human Neutrophils In Vitro. Among These Compounds,6-[2-(3,4-Diethoxyphenyl)Thiazol-4-Yl]-Pyridine-2-Carboxylic Acid (Opc-6535) Was Selected As One Of The Most Promising Compounds. The Synthesis And Structure-Activity Relationships Of These Compounds Are Reported Herein.
Doi:10.1021/jm00002A017