CAS: 138-65-8; Noradrenaline

上下游产品

CAS号104819-57-0 R,S-2,2'-dinitr... | CAS号5090-29-9 2-氨基-3',4'-二羟基苯乙酮盐酸盐 | CAS号409109-83-7 DL-erythro-pent... | CAS号51-61-6 多巴胺 | CAS号67632-28-4 2-bromo-1-(3,4-... | CAS号72712-21-1 乙酸2-乙酰氧基-5-乙酰基-苯酯 | CAS号120-80-9 邻苯二酚 | CAS号645-36-3 氨基乙醛缩二乙醇 | CAS号499-61-6 2-amino-1-(3,4-... | CAS号14309-96-7 4-(2-amino-1-hy... | CAS号50-53-3 氯丙嗪 | CAS号149-95-1 L-去甲肾上腺素 | CAS号51-41-2 去甲肾上腺素 | CAS号15069-79-1 5,6-二乙酰氧基吲哚 | CAS号3569-19-5 5,6,3-trihydrox... | CAS号490-89-1 noradren°Chrome | CAS号5707-55-1 Dopal | CAS号3770-01-2 DL-β-O-甲基去甲肾上腺素盐酸盐

📜2-氨基-1-(3,4-二羟基苯基)乙烷-1-酮置于sodium Amalgam体系中,化学反应生成Dl-去甲肾上腺素
参考文献:De157300
标题:De157300

专利信息

专利号:WO-2025040359-A1
优先权日:2023-08-24
标题:Method for the synthesis of (1r)-2-(dibenzylamino)-1-(3,4-dibenzyloxyphenyl)ethanol, novel intermediates of said method and use of the product in the synthesis of noradrenaline
发明人：SÃ?NCHEZ CASALS CARLES; JIMÉNEZ ALONSO OSCAR; BALLETTE ROBERTO
权利人:MOEHS IBERICA SL; HELM PORTUGAL UNIPESSOAL L D A
摘要:The invention relates to a method for the synthesis of (1R)-2-(dibenzylamino)-1-(3,4- dibenzyloxyphenyl)ethanol of formula (I): (I), to said compound of formula (I), and to the use thereof as an intermediate in the synthesis of noradrenaline.

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-2004249170-A1
优先权日:2002-01-24
标 题 :Process for preparing an intermediate useful for the asymmetric synthesis of duloxetine
发明人：BORGHESE ALFIO
摘要:This invention provides a process for the synthesis of(S)-3-Methylamino-1-2-thienyl)-1-propanol, a key intermediate in the synthesis of duloxetine.

专利号:US-6479549-B2
优先权日:2000-02-28
标 题:Carnosic acid derivatives for promoting synthesis of nerve growth factor
发明人：KOSAKA KUNIO; MIYAZAKI TOSHITSUGU; YOKOI TOSHIO
权利人:NAGASE & CO LTD
摘要:A novel carnosic acid derivative for promoting the synthesis of nerve growth factor (NGF), a composition comprising the carnosic acid derivative as an effective ingredient, as well as, a method of promoting the synthesis of NGF comprising administering an effective amount of the carnosic acid derivative as an effective ingredient to a subject requiring such promotion. The carnosic acid derivative, composition and method according to the present invention can safely and efficiently promote the production of NGF in the living body, without being accompanied by a side effect such as a loss of a quantitative balance of hormones in the living body.

专利号:US-8791287-B2
优先权日:2010-07-02
标 题:Process for the synthesis of tapentadol and intermediates thereof
发明人：MOTTA GIUSEPPE; VERGANI DOMENICO; BERTOLINI GIORGIO; LANDONI NICOLA
权利人:MOTTA GIUSEPPE; VERGANI DOMENICO; BERTOLINI GIORGIO; LANDONI NICOLA; EUTICALS SPA
摘要:The object of the present invention is a new process for the synthesis of tapentadol, both as free base and in hydrochloride form, which comprises the step of alkylation of the ketone (VII) to yield the compound (VIII), as reported in Diagram 1, with high stereoselectivity due to the presence of the benzyl group as substituent of the amino group. It was surprisingly found that this substitution shifts the keto-enol equilibrium towards the desired enantiomer and amplifies the capacity of the stereocenter present in the compound (VII) to orient the nucleophilic addition of the organometallic compound at the carbonyl towards the desired stereoisomer. This substitution thus allows obtaining a considerable increase of the yields in this step, and consequently allows significantly increasing the overall yield of the entire tapentadol synthesis process. n A further object of the present invention is constituted by the tapentadol free base in solid form, obtainable by means of the process of the invention. n Still another object of the invention is represented by the crystalline forms I and II of the tapentadol free base. n A further object of the present invention is the mixture of the crystalline forms I and II of the tapentadol free base.

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.