环戊烷 反应 24.0H,反应生成环戊酮肟 参考文献:Mackor,A.; De Boer,T.J.,Recueil Des Travaux Chimiques Des Pays-Bas,1970,Vol. 89,P. 151-158 标题:Mackor,A.; De Boer,T.J.,Recueil Des Travaux Chimiques Des Pays-Bas,1970,Vol. 89,P. 151-158
专利信息
专利号:US-6770763-B2 优先权日:2002-06-11 标题 :Asymmetric synthesis of amino-pyrrolidinones 发明人:MAGNUS NICHOLAS A; CONFALONE PASQUALE N; SAVAGE SCOTT A; YATES MATTHEW; WALTERMIRE ROBERT E; MELONI DAVID J; CAMPAGNA SILVIO 权利人:BRISTOL MYERS SQUIBB CO 摘要:A novel process for the asymmetric synthesis of an amino-pyrrolidinone of the type shown below from appropriate pyrrolidinones is described.These compounds are useful as intermediates for MMP and TACE inhibitors.
专利号:WO-8911473-A1 优先权日:1988-05-27 标 题:Process for the synthesis of o-substituted oxime compounds 发明人:CHEMPOLIL THOMAS MATHEW 权利人:ALLIED SIGNAL INC 摘要:A novel process for the production of O-substituted oximes is disclosed. The process involves reacting an oxime with an alkali-metal hydroxide optionally in a solvent which forms an azeotrope with water to form a mixture of the alkali metal salt of the oxime and water, removing all or a portion of the water by distilling the mixture azeotropically and reacting the distilled mixture with an alpha halo carboxylic acid.
专利号:US-4365027-A 优先权日:1981-12-28 标 题 :Removal of acrylonitrile from latex with oximes 发明人:SENYEK MICHAEL L; COSTANZA ALBERT J 权利人:GOODYEAR TIRE & RUBBER 摘要:Acrylonitrile is a monomer that is widely used in the synthesis of a vast variety of polymers. Undesirable quantities of unpolymerized residual acrylonitrile are often present in these acrylonitrile polymers. This residual or free acrylonitrile dissolved in an acrylonitrile polymer and/or its emulsifier system and the water phase used in its polymerization can be reduced significantly in concentration by treatment with oximes. Oximes react with acrylonitrile by an oxygen-cyanoethylation reaction which results in the formation of a cyanoethyl oximino ether linkage.
专利号:US-5766887-A 优先权日:1996-08-26 标题 :Synthesis of 9-0-acetyl N-acetylneuraminic acid oligosaccharides 发明人:WONG CHI-HUEY; TAKAYAMA SHUICHI 权利人:SCRIPPS RESEARCH INST 摘要:Regioselective acetylation of the 9-hydroxyl group on N-acetylneuraminic acid is achieved enzymatically for producing oligosaccharides which contain a terminal N-acetylneuraminic acid moiety. This method provides access to O-acylated disialogangliosides as well as other N-acetyl-neuraminic acid oligosaccharides. These compounds are biologically and medicinally important and are difficult to obtain from nature or by chemical acylations. The methodology affords simple reaction conditions and minimal purification steps. In addition, the process affords good yields and the enzymes and reagents employed are commercially available with high stability and low costs.
专利号:US-2003236401-A1 优先权日:2002-06-11 标 题:Asymmetric synthesis of amino-pyrrolidinones
专利号:US-2770643-A 优先权日:1953-11-05 标题:Synthesis of aliphatic nitriles by pyrolysis and thermal cleavage of hydrazones, ketazines, ketimines and ketoximes 发明人:ANDERSON JOHN L 权利人:DU PONT