专利号:US-9738647-B2 优先权日:2009-12-24 标题:Methods for the synthesis of polycyclic guanidine compounds 发明人:GRIDNEV ALEXEI 权利人:NOVOMER INC; SAUDI ARAMCO TECH CO 摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.
专利号:US-7834174-B2 优先权日:2004-09-10 标 题 :Per-6-guanidino-, alkylamino-cyclodextrins, methods of their synthesis and their use for the compaction of DNA and intercellular delivery 发明人:MAVRIDIS IRENE M; YANNAKOPOULOU KONSTANTINA; ELIADOU KYRIAKI; MOURTZIS NIKOLAOS; AGGELIDOU CHRYSI 权利人:MAVRIDIS IRENE M; YANNAKOPOULOU KONSTANTINA; ELIADOU KYRIAKI; MOURTZIS NIKOLAOS; AGGELIDOU CHRYSI 摘要:The invention relates to new compounds of type hexakis(6-deoxy-6-NH(CH 2 ) n —R 1 )α-cyclodextrin and heptakis(6-deoxy-6-NH(CH 2 ) n —R 1 )-(β-cyclodextrin, and octakis(6-deoxy-6-NH(CH 2 ) n —R 1 )-γ-cyclodextrin, where n=2-6 when R 1 =NH 2 and n=0 when R 1 =C(â•?NH)NH 2 and n=2-6 when R 1 =NH—C(â•?NH)NH 2 and their use in the compaction of DNA and in cell permeation. The invention also relates to methods of synthesis of the above compounds.
专利号:US-12303865-B2 优先权日:2022-10-10 标 题 :Aqueous manufacture of aminated MOF complexes 发明人:GOSSELIN AERI; GAMORAS JOEL H; HERM ZOEY ROSE; MCDONALD THOMAS M; WENZ GRAHAM B; ZHU LINA 权利人:MOSAIC MAT INC 摘要:This disclosure relates to a select class of porous adsorbent, metal-organic frameworks (MOFs) capable of adsorbing carbon dioxide, their manufacturing, applications, and methods of use. Specifically, this disclosure relates to the solvo(hydro)thermal synthesis of a family of metal-organic frameworks, and their subsequent processing and transformation into material forms suitable for use in acid gas separations. More specifically, this disclosure relates to the preparation and recovery of MOFs at multiple scales of production, demonstrating the suitability and robustness of the materials thus obtained by the disclosed synthetic route and post-synthetic manipulation employed to tailor the materials for use in a variety of commercial acid gas separation systems, with improved performances, recyclability, and reuse characteristics.
专利号:US-6689919-B1 优先权日:1999-09-22 标 题 :Catalysts for oxidative polymerization of fluorophenol, method of oxidative polymerization of fluorophenol, and poly(oxyfluorophenylene) derivative 发明人:TSUCHIDA EISHUN; OYAIZU KENICHI; KUMAKI YOSUKE; SAITO KEI 权利人:JAPAN SCIENCE & TECH CORP 摘要:The synthesis of fluoropolyarylene ether with a high degree of polymerization is enabled, by using a copper complex catalyst with an oxidation potential in the range of -1V to 2V, for the oxidative polymerization of fluorophenols that contain at least one hydrogen atom as well as a fluorine atom bonded to the carbon atoms constituting the benzene ring.
专利号:WO-2015131100-A1 优先权日:2014-02-28 标题:Ligand-controlled c(sp3)-h arylation and olefination in synthesis of unnatural chiral alpha amino acids 发明人:YU JIN-QUAN 权利人:SCRIPPS RESEARCH INST 摘要:The use of ligands to tune the reactivity and selectivity of transition metal-catalysts for C(-sp3)-H bond functionalization is a central challenge in synthetic organic chemistry. Herein, we report a rare example of catalyst-controlled C(sp3)-H arylation using pyridine and quinoline derivatives: the former promotes exclusive monoarylation, whereas the latter activates the catalyst further to achieve diarylation. Successive application of these ligands enables the sequential diarylation of a methyl group in an alanine derivative with two different aryl iodides, affording a wide range of β-Ar-p-Ar ' -cc-amino acids with excellent levels of diastereoselectivity (d.r. > 20:1). Both configurations of the β-chiral center can be accessed by choosing the order in which the aryl groups are installed. The use of a quinoline derivative as a ligand also enables C(sp3)-H olefination of a protected alanine.
专利号:US-8541191-B2 优先权日:2008-08-29 标 题 :Hydrolases, nucleic acids encoding them and methods for biocatalytic synthesis of structured lipids 发明人:DAYTON CHRISTOPHER L G; HITCHMAN TIM; KLINE KATIE; LYON JONATHAN; WALL MARK A; BARTON NELSON R 权利人:DAYTON CHRISTOPHER L G; HITCHMAN TIM; KLINE KATIE; LYON JONATHAN; WALL MARK A; BARTON NELSON R; BUNGE OILS INC 摘要:Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity, e.g., lipases, saturases, palmitases and/or stearatases and methods for preparing low saturate or low trans fat oils, such as low saturate or low trans fat animal or vegetable oils, e.g., soy or canola oils.