CAS: 90580-64-6; 2-Amino-3-(4-Boronophenyl)Propanoic Acid

该化合物是苯丙胺的碳酸衍生物,主要用于有机合成和药用化学,其主要优势在于其作为铃木-Miyaura交叉组合反应的多用途中间体的作用,有助于形成碳-碳结,用于复杂的分子构造; 碱酸味可增强反应性,同时在受控制的条件下保持稳定性; 该化合物在化改变和研制含有含有肉的治疗器,包括蛋白抑制剂方面特别宝贵; 其种族形式(dl-)允许更广泛的合成灵活性; 该产品的特点在于它与水溶剂和有机溶剂的兼容性,使之适合多种反应环境; 建议在惰性条件下进行适当处理,以保持其再活性.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

N-acetyl-4-dihydroxyboranyl-phenylalanineN-acetyl-4-dihydroxyboranyl-phenylalanine 3-[4-(thien-3-yl)phenyl]alanine 2-amino-3-(2'-fluoro-biphenyl-4-yl)-propionic acid 2-benzyloxycarbonylamino-3-(4-boronophenyl)propionic acid

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于sodium Hydroxide体系中,化学反应生成 4-二羟基硼基-Dl-苯丙氨酸
    参考文献:Synthesis Of Aromatic Boronic Acids. Aldehydo Boronic Acids And A Boronic Acid Analog Of Tyrosine1
    标题:Synthesis Of Aromatic Boronic Acids. Aldehydo Boronic Acids And A Boronic Acid Analog Of Tyrosine1
    摘要:
    DOI:10.1021/ja01537A021

    海关参考信息

    专利信息


    专利号:US-2008299666-A1
    优先权日:2007-06-01
    标 题 :Novel Peptide-Based Borono-Lectin (PBL) Sensors
    发明人:LAVIGNE JOHN J; THOMPSON PAUL R
    权利人:UNIV SOUTH CAROLINA
    摘要:Peptide-based borono-lectin sensors, along with their synthesis and analysis and methods of use, are generally described. These sensors use peptides as a scaffold and introduce boronic acid moieties onto the peptide scaffold as the binding site for the targeted analyte (e.g., carbohydrates, glycans, etc.). The boronic acid moieties can be arranged on the protein scaffold in such a manner that a particularly targeted carbohydrate or glycoprotein will bond to the protein scaffold via the boronic acid functionality. Such bonding can indicated the presence or absence of that targeted analyte in the sample.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Direct Synthesis Of Unprotected 4-Aryl Phenylalanines Via The Suzuki Reaction Under Microwave Irradiation
    作者:Yong Gong,Wei He |发布日期:2002.10.1
    摘要:[formula: See Text] 4-Aryl Phenylalanines Were Prepared As Free Amino Acids From The Suzuki Coupling Of 4-Borono Phenylalanine With Aryl Halides In High Yields Within 5-10 Min Under Microwave Irradiation.

    合成参考文献

    参考DOI号:10.1055/s-1999-3624
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