CAS: 81335-37-7; Imazaquin

该化合物是一种选择性除草剂,主要用于控制某些大叶和草杂草,特别是大豆和大米,属于被称为imidazolinones的化学品类别,其功能包括抑制对植物中基本氨基酸合成至关重要的酶乙酸合成,Imazaquin的特点是其系统性行动,允许植物根部和树叶吸收,从而实现有效的杂草管理,该化合物通常根据目标杂草和作物类型,在出现前或出现后施用.已知该化合物对哺乳动物和鸟类的毒性相对较低,因此在农业环境中是一种首选.然而,与许多除草剂一样,它对非目标植物物种和水生环境构成风险,需要谨慎应用和遵守安全准则.该化合物的环境持久性和土壤流动性也是其使用中的重要考虑因素.

结构式图片

欧盟法规

[欧盟农药活性物质

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CAS号40963-14-2 2-氨基-2,3-二甲基丁酰胺 | CAS号32413-08-4 2,3-喹啉二甲酸二乙酯

合成工艺路线路线简述

    2-氨基-2,3-二甲基丁酰胺 以 四氢呋喃,Sodium Hydroxide,水 作为反应溶剂,化学反应生成 灭草喹
    参考文献:2-(2-Imidazolin-2-yl)-Pyridines And Quinolines,Process And
    标题:2-(2-Imidazolin-2-yl)-Pyridines And Quinolines,Process And
    摘要:提供了新型2-(2-咪唑啉-2-基)吡啶和喹啉化合物,以及其制备的过程和中间体化合物,以及用于控制各种一年生和多年生植物物种的方法.

    海关参考信息

    专利信息


    专利号:US-8735586-B2
    优先权日:2007-06-26
    标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
    发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
    权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

    专利号:EP-2173747-B1
    优先权日:2007-06-26
    标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
    发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
    权利人:SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

    专利号:US-6861531-B2
    优先权日:2002-03-27
    标 题:Synthesis of 2,6-dicarbonylpyridines
    发明人:GATELY DANIEL A
    权利人:BOULDER SCIENT CO
    摘要:Synthesis of 2,6-dicarbonylpyridines in solution in a hydrocarbon medium is described. The solutions of 2,6-dicarbonylpyridines may be used directly in further syntheses.

    专利号:US-2022089618-A1
    优先权日:2019-01-29
    标题:Solid-State Synthesis Of Precursors Of Metal-Organic Frameworks
    发明人:MAJANO GERARDO J; FALKOWSKI JOSEPH M
    权利人:EXXONMOBIL RES & ENG CO
    摘要:Metal-organic frameworks (MOFs) are highly porous entities comprising a multidentate ligand coordinated to multiple metal atoms, typically as a coordination polymer. MOFs are usually produced from a solvent in powder form under hydrothermal or solvothermal synthesis conditions. Alternately, powder-form precursors of MOFs may be formed by milling or mulling a substantially solid mixture of a metal salt and a multidentate organic ligand, optionally in the presence of a small amount of a solvent. The powder-form precursors may then undergo heating, typically in the absence of applied shear, to produce the corresponding MOF. Mulling may be differentiated from milling at least in that mulling applies to the substantially solid mixture at a non-constant pressure and milling applies a constant pressure while forming the powder-form precursor. In some cases, mulling may promote more effective formation of the powder-form precursor compared to milling.

    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.
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    主要参考文献


    1: Wang D, Zhang Q, Zheng Y, Lin D, Yu Y. Estimating the combined toxicity of flufenacet and imazaquin to sorghum with pore water herbicide concentration. J Environ Sci (China). 2016 Mar;41:154-61. doi: 10.1016/j.jes.2015.04.031. Epub 2015 Aug 29. doi: 10.1021/acs.jafc.5b04663. Epub 2015 Dec 9. doi: 10.1021/acs.jafc.5b04093. Epub 2015 Oct 23. doi: 10.1093/ije/dyv195. Epub 2015 Sep 27.
    5: Kemmerich M, Bernardi G, Adaime MB, Zanella R, Prestes OD. A simple and efficient method for imidazolinone herbicides determination in soil by ultra-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2015 Sep 18;1412:82-9. doi: 10.1016/j.chroma.2015.08.005. Epub 2015 Aug 6. doi: 10.1016/j.jconhyd.2015.02.002. Epub 2015 Feb 12. doi: 10.1007/s11356-014-3757-z. Epub 2014 Oct 30. doi: 10.1016/j.pestbp.2013.05.013. Epub 2013 Jun 1. doi: 10.1016/j.jcis.2013.10.024. Epub 2013 Oct 26. doi: 10.1016/j.jcis.2011.04.055. Epub 2011 Apr 27. doi: 10.1007/s00128-010-0076-z. Epub 2010 Jul 21. doi: 10.1016/j.chemosphere.2010.03.046. Epub 2010 Apr 22. doi: 10.1016/j.chroma.2009.04.080. Epub 2009 May 3. doi: 10.1002/elps.200800696. Chinese. doi: 10.1016/j.chemosphere.2008.11.077. Epub 2009 Jan 9. doi: 10.1080/09593330801983516. doi: 10.1080/03601230701794968.

    合成参考文献


    摘要:Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan., 24(245), 1999
    摘要:Farm Chemicals Handbook 1992. Willoughby, OH: Meister Publishing Co., 1992., p. C-299
    摘要:Hartley, D. and H. Kidd (eds.). The Agrochemicals Handbook. 2nd ed. Lechworth, Herts, England: The Royal Society of Chemistry, 1987., p. Aug 87
    参考文献:10.1007/s002440010196
    摘要:P. DiVincenzo, D. L. Sparks J. Sorption of the Neutral and Charged Forms of Pentachlorophenol on Soil: Evidence for Different Mechanisms. Archives of Environmental Contamination and Toxicology. 2001 Apr 01;40(4):445–50. doi: 10.1007/s002440010196.
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