CAS: 4521-31-7; (2-Mercaptophenyl)Methanol

该化合物是一种有机化合物,其特征是,乙醇(-SH)和羟基(-OH)功能组都附于苯环,其分子结构具有一种苯基环,在与苯基酒精混合物相对的正方位上,以甲卡普托组取代苯基环.该化合物一般没有颜色,可粉色黄色液体,有明显的气味.它溶于有机溶剂和水中表现出中等溶解性,因为存在氢氧基组. 2-甲基甲基丙基苯乙烯乙醇因其抗氧化性特性而闻名,可以作为各种化学反应中的消毒剂.此外,该化合物在合成药物,农业化学品和作为协调化学的离子体中具有应用.安全考虑包括:由于具有潜在的刺激效应,需要使用适当的个人防护设备来处理它.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号4892-02-8 硫代水杨酸甲酯 | CAS号147-93-3 硫代水杨酸 | CAS号33384-77-9 (2-甲基磺酰基苯基)-甲醇 | CAS号1074-01-7 dithiosalicylic acid | CAS号59130-11-9 6-methylidenecy... | CAS号39161-85-8 2-疏基苯乙酸 | CAS号35190-71-7 (2-([2-(羟基甲基)苯基... | CAS号191404-57-6 8-[2-(hydroxyme... | CAS号217962-06-6 2-[[bis(pyridin... | CAS号31910-65-3 3H-2,1λ4-benzox... | CAS号33384-77-9 (2-甲基磺酰基苯基)-甲醇 | CAS号35190-71-7 (2-([2-(羟基甲基)苯基... | CAS号1195-14-8 2-甲基苯并[b]噻吩 | CAS号137105-47-6 5-METHOXY-QUINA... | CAS号14092-00-3 2-甲苄基硫醇 | CAS号22913-24-2 甲基苯并噻吩-2-甲醛 | CAS号36634-77-2 2-(2-phenylethe...

合成工艺路线路线简述

  • 合成目标产物 2-Mercaptobenzyl Alcohol 主要起始原料 Thiosalicylic Acid
  • (文献来源)合成步骤主要原料 Thiosalicylic Acid
📜硫代水杨酸置于lithium Aluminium Tetrahydride体系中,用 乙醚 作为反应溶剂,化学反应生成 2-巯基苯甲醇
参考文献:催化分子内stetter反应对映体选择性形成四元立体中心
标题:催化分子内stetter反应对映体选择性形成四元立体中心
摘要:使用催化的分子内stetter反应已经完成了四元立体中心的不对称形成.各种束缚的醛和michael受体以优异的收率和对映选择性被环化.
DOI:10.1016/j.Tet.2006.06.042

海关参考信息

专利信息


专利号:US-9593142-B2
优先权日:2013-12-26
标题 :Aldehyde capture ligation technology for synthesis of amide bonds
发明人:ARORA PARAMJIT S; RAJ MONIKA; WU HUABIN
权利人:ARORA PARAMJIT S; RAJ MONIKA; WU HUABIN; UNIV NEW YORK
摘要:The present invention relates to ligation agents and their use in making an amide ligation product. Methods of making the ligation agents are also disclosed.

专利号:US-4801665-A
优先权日:1986-12-30
标 题:Resin method for making sulfoxide for solid phase peptide synthesis
发明人:GETMAN DANIEL P; HEINTZ ROBERT M
权利人:MONSANTO CO
摘要:A resin for solid phase peptide synthesis and a method for synthesizing the resin wherein the resin has a sulfoxide linkage which is stable to strong acid deprotecting conditions. The linkage can be reduced to a sulfide linkage which allows cleavage of the peptide from the resin under mild acid conditions.

专利号:US-4764594-A
优先权日:1987-03-30
标题 :Resin support for solid phase peptide synthesis
发明人:GETMAN DANIEL P
权利人:MONSANTO CO
摘要:A resin and method for preparing the resin for solid phase peptide synthesis. The resin has a sulfoxide linkage, which is stable to strong acid conditions. The sulfoxide linkage can be reduced to a sulfide linkage, which allows cleavage of the peptide from the resin under mild acid conditions.

专利号:US-2015232504-A1
优先权日:2013-12-26
标题 :Aldehyde capture ligation technology for synthesis of amide bonds

专利号:US-2017247324-A1
优先权日:2013-12-26
标题 :Aldehyde capture ligation technology for synthesis of amide bonds

专利号:US-9522901-B2
优先权日:2005-05-26
标题:Compositions and methods including cell death inducers and procaspase activation
发明人:HERGENROTHER PAUL J; PUTT KARSON S; PETERSON QUINN P; FAKO VALERIE
权利人:UNIV ILLINOIS
摘要:Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed in connection with modification of procaspases such as procaspase-3. In embodiments, compositions are capable of activation of procaspase-3.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: Herbert Meier, Et Al. Benzoxetes And Benzothietes--Heterocyclic Analogues Of Benzocyclobutene. Molecules. 2012 Feb 7;17(2):1548-70.

合成参考文献


参考文献:10.1038/sj.bjc.6605810
摘要:Peng G, Hakim M, Broza YY, Billan S, Abdah-Bortnyak R, Kuten A, Tisch U, Haick H. Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors. British Journal of Cancer. 2010 Jul 20;103(4):542–51. doi: 10.1038/sj.bjc.6605810.
摘要:Rakitin, O. A., Science of Synthesis, (2007) 31, 956.
摘要:Avilov, D.; Dittmer, D., Science of Synthesis, (2007) 33, 296.
摘要:Virieux, D.; Volle, J.-N.; Pirat, J.-L., Science of Synthesis, (2009) 42, 543.
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