专利号:US-11970694-B2 优先权日:2009-10-22 标题 :Rapid display method in translational synthesis of peptide 发明人:KASHIWAGI KENJI; REID PATRICK 权利人:PEPTIDREAM INC 摘要:Provided are linkers suitable for preparing a conjugate of a nucleic acid and a peptide as a translation product thereof in a reconstituted cell-free translation system in genotype-phenotype mapping (display methods), said linkers comprising a single-stranded structure region having a side chain base pairing with the base at the 3′-end of an mRNA at one end and a peptidyl acceptor region containing an amino acid attached to an oligo RNA consisting of a nucleotide sequence of ACCA via an ester bond at the other end, characterized in that the ester bond is formed by using an artificial RNA catalyst. Also provided are display methods using [mRNA]-[linker]-[peptide] conjugates assembled via such linkers.
专利号:SE-8904215-D0 优先权日:1989-12-14 标题 :THE SYNTHESIS OF A D-AMINO ACID ESTER IN AN ORGANIC MEDIA WITH CHYMOTRYPSIN MODIFIED BY A BIO IMPRINTING PROCEDURE
专利号:US-2022047711-A1 优先权日:2018-12-10 标题 :Photocrosslinking peptides for site specific conjugation to fc-containing proteins 发明人:SADOWSKY JACK; ZACHARIAS NEELIE TYANA 权利人:GENENTECH INC 摘要:Provided herein are peptides having a photocrosslinking moiety useful for the synthesis of antibody-drug conjugates as well as methods of making and using such conjugates.
专利号:EP-0685442-A1 优先权日:1994-05-27 标题:Reagent and process for the Synthesis of esters and transesterifiable xanthates
专利号:SE-8904215-L 优先权日:1989-12-14 标 题 :SYNTHESIS OF A D-AMINO ACID ESTER IN AN ORGANIC SOLVENT WITH CHYMOTRYPSIN MODIFIED WITH A BIOMOLECYCLERIC PRINTING METHOD.
专利号:EP-2517722-B1 优先权日:2003-05-15 标 题:Synthesis of diketopiperazines