CAS: 20781-21-9; (2,4-Dimethoxyphenyl)Methanamine Hydrochloride

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CAS号20781-20-8 2,4-二甲氧基苄胺 | CAS号93489-13-5 2,4-二甲氧苄基异氰酸酯

2,4-二甲氧基苯甲腈置于potassium Tert-Butylate,2C16H18Mnn2O4(1+)*c32H32Mn2N4O6(2+)*4Cf3O3S(1-)*2H2O,Sodium Hydroxide,盐酸体系中,用 四氢呋喃,甲醇,乙酸乙酯 用作溶剂,以68 %的收率获得2,4-二甲氧基苄胺盐酸盐
参考文献:具有结构特征的锰 (III)-Salen 络合物的催化命运,使用氢硅烷将伯酰胺有效转化为胺或腈
标题:具有结构特征的锰 (III)-Salen 络合物的催化命运,使用氢硅烷将伯酰胺有效转化为胺或腈
摘要:通过使用简单的定义明确的 O,N,N,O 供体基于沙仑的地球丰富的锰 ( Iii) 复合物在温和条件下.通过添加封端剂仲酰胺稍微改变反应条件,伯酰胺向胺的转化在中间腈态停止(9 个例子).同样的催化剂也有能力使用廉价的硅烷如聚甲基氢硅氧烷 (Pmhs) 将腈还原为胺(15 个例子).还进行了机理研究和 Dft 计算,以了解反应机理和化学选择性.在这种催化转化中,锰催化剂激活伯酰胺,整个还原过程通过伯酰胺脱水为相应的腈,然后还原为相应的伯胺.
Doi:10.1039/d3Nj01183F

专利信息

专利号:US-5849951-A
优先权日:1995-03-01
标题 :Synthesis of carboxylic and hydroxamic acid derivatives
发明人：FLOYD CHRISTOPHER DAVID; WHITTAKER MARK
权利人:BRITISH BIOTECH PHARM
摘要:PCT No. PCT/GB96/00467 Sec. 371 Date Aug. 29, 1997 Sec. 102(e) Date Aug. 29, 1997 PCT Filed Mar. 1, 1996 PCT Pub. No. WO96/26918 PCT Pub. Date Sep. 6, 1996A method for the preparation of a compound of formula (I) (I) wherein X is hydrogen; Y is (i) a group -CO2R5 wherein R5 is a carboxyl protecting group or (ii) a group -CONR6OR7 wherein R6 is an amino protecting group and R7 is a hydroxyl protecting group; and S1, S2, S3 and S4 each represent covalently bound moieties which are substantially non-reactive with the reaction components (II), (III), or (IV) defined below, which method comprises causing the co-condensation in a liquid organic medium of a carboxylic acid reaction component of formula (II); an aldehyde of formula (IIIA); ammonia; and an isonitrile reaction component of formula (IV): (II) (IIIA) (IV) wherein Y, S1, S2, S3 and S4 are as defined with respect to formula (I).

专利号:WO-9626918-A1
优先权日:1995-03-01
标题:Synthesis of carboxylic and hydroxamic acid derivatives

专利号:US-4541955-A
优先权日:1980-09-15
标 题 :Azetidinone-4-carboxylate containing a protected 3-acetyl group and process for their preparation
发明人：LEMPERT KAROLY; HAERSANYI KALMAN; DOLESCHALL GABOR; HORNYAK GYULA; NYITRAI JOZSEF; ZAUER KAROLY; FETTER JOZSEF; SIMIG GYULA; VISKY NEE GOMBOS ZSUZSANNA; BARTA NEE SZALAI GIZELLA
权利人:RICHTER GEDEON VEGYESZET
摘要:The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particularly, the invention concerns new compounds of the Formula (V) ##STR1## wherein R is a group suitable for the protection of amides; n Z is alkyl; and n Y 1 and Y 2 together form a group suitable for temporary protection of a keto group. The new compounds are valuable intermediates in the synthesis of thienamycin.

专利号:EP-0812312-A1
优先权日:1995-03-01
标题:Synthesis of carboxylic and hydroxamic acid derivatives

专利号:US-6995142-B2
优先权日:1998-04-30
标题 :Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
发明人：DRAGOVICH PETER SCOTT; WEBBER STEPHEN EVAN; PRINS THOMAS JAY; ZHOU RU; MARAKOVITS JOSEPH TIMOTHY; JOHNSON JR THEODORE O
权利人:AGOURON PHARMA
摘要:Peptido and peptidomimetic compounds of the formula: n nwherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.

专利号:JP-H11501025-A
优先权日:1995-03-01
标 题:Synthesis of derivatives of carboxylic and hydroxamic acids