CAS: 136779-27-6; ()-1,2-Bis[(2S,5S)-2,5-Diethylphospholano]Ethane

上下游产品

CAS号129619-37-0 (3R,6R)-3,6-辛二醇 | CAS号5518-62-7 1,2-双(膦酰)乙烷

📜(3R,6R)-3,6-辛二醇置于ruthenium Trichloride,Sodium Periodate,氯化亚砜体系中,化学反应生成(-)-1,2-双[(2S,5S)-2,5-二乙基膦烷基]乙烷
参考文献:C2-Symmetric Bis(Phospholanes) And Their Use In Highly Enantioselective Hydrogenation Reactions
标题:C2-Symmetric Bis(Phospholanes) And Their Use In Highly Enantioselective Hydrogenation Reactions
摘要:
Doi:10.1021/ja00022A047

专利信息

专利号:US-6891059-B2
优先权日:2000-01-27
标题:Asymmetric synthesis of pregabalin
发明人：BURK MARK JOSEPH; GOEL OM PRAKASH; HOEKSTRA MARVIN SIMON; MICH THOMAS FREDERICK; MULHERN THOMAS; RAMSDEN JAMES A
权利人:WARNER LAMBERT CO
摘要:This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin.

专利号:NZ-519551-A
优先权日:2000-01-27
标题:Asymmetric synthesis of pregabalin

专利号:US-2003212290-A1
优先权日:2000-01-27
标 题 :Asymmetric synthesis of pregabalin

专利号:IL-150633-A
优先权日:2000-01-27
标题:Asymmetric synthesis of pragabalin and its new intermediates

专利号:OA-12167-A
优先权日:2000-01-27
标 题 :Asymmetric synthesis of pregabalin.

专利号:WO-0155090-A1
优先权日:2000-01-27
标 题 :Asymmetric synthesis of pregabalin