CAS: 1088496-42-7; (6-(2-Hydroxypropan-2-yl)Pyridin-3-yl)Boronic Acid

该化合物是一种有机有机体化合物,其特征是附于一个环上的碳酸功能组;该化合物具有增强溶解性和再活性的氢氧化甲基替代成分;其与二醇形成可逆共价联系的能力为人所知,使其在包括有机合成和药用化学在内的各种应用中具有价值;环有助于化合物的芳香性并能够参与协调化学;此外,氢氧化硫组的存在可能会影响化合物的生物活动以及与其他分子的相互作用;该物质通常用于研究环境,特别是用于研制基于博伦的试剂和催化剂;其独特的结构特征使其能够在复杂的有机分子合成和生物系统研究中发挥作用,特别是在药物开发和分子识别过程中发挥作用.

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上下游产品

5-bromo-N-methyoxy-N-methylpyridine-2-carboxamide 1-(5-bromopyridin-2-yl)ethanone 5-bromoisonicotinic acid bis(pinacol)diborane

合成工艺路线路线简述

    📜5-溴-2-吡啶羧酸置于1,1'-双(二苯膦基)二茂铁二氯化钯(II)二氯甲烷复合物,Potassium Acetate,N,N-二异丙基乙胺,Methanaminium,N-[(Dimethylamino)(3H-1,2,3-Triazolo[4,5-B]Pyridin-3-Yloxy)Methylene]-N-Methyl-,Hexafluorophosphate(1-)体系中,用 四氢呋喃,1,4-二氧六环,N,N-二甲基甲酰胺 用作溶剂,化学反应 2.0H,反应生成6-(2-羟基丙烷-2-基)吡啶-3-硼酸
    参考文献:Use Of Pyrazolopyrimidine Derivatives For The Treatment Of Pi3K-Delta Related Disorders
    标题:Use Of Pyrazolopyrimidine Derivatives For The Treatment Of Pi3K-Delta Related Disorders
    摘要:本申请提供了使用以下化合物治疗pi3Kδ相关疾病的方法: 或其药用盐的方法.

    专利信息


    专利号:US-11225655-B2
    优先权日:2010-04-16
    标题:Bi-functional complexes and methods for making and using such complexes
    发明人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
    权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
    摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

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