CAS: 106486-76-4; Azinomycin B

专利信息

专利号:WO-9502566-A1
优先权日:1993-07-16
标题 :Synthesis of combinatorial arrays of organic compounds through the use of multiple component combinatorial array syntheses
发明人：ARMSTRONG ROBERT W
权利人:UNIV CALIFORNIA; ARMSTRONG ROBERT W
摘要:The present invention relates to an array of compounds having a common core structure wherein the compounds of the array comprise the products of a multiple component combinatorial array synthesis having at least three components. The present invention also relates to the method of synthesizing that array. A further embodiment of the present invention relates to the use of solid phase synthesis to synthesize the combinatorial array of compounds. The present invention also relates to a method of creating a combinatorial array of compounds with a common core structure by identifying the desired core structure, identifying an MCCA reaction capable of generating that core structure, followed by preparing an array of compounds using the identified MCCA reaction according to the aforementioned method. The present invention also relates to a method for conducting in vitro assays of biological material using the combinatorial arrays of the present invention.

专利号:US-10472663-B2
优先权日:2015-01-21
标 题:Procedure for the rapid determination of bacterial susceptibility to antibiotics that inhibit protein synthesis
发明人：FERNÃ?NDEZ GARCÃ?A JOSÉ LUIS; GOSÃ?LVEZ BERENGUER JAIME; BOU ARÉVALO GERMÃ?N; TAMAYO NOVAS MARIA; SANTISO BRANDARIZ REBECA; OTERO FARIÑA FÃ?TIMA MARÃ?A
权利人:ABM TECH LLC
摘要:The present invention relates to a method for the rapid evaluation of bacterial susceptibility or non-susceptibility of bacteria to antibiotics that inhibit protein synthesis. The rationale is to identify bacterial responses that depend or are influenced by protein synthesis. If this response is prevented or reduced by the antibiotic that inhibits the protein synthesis, the bacteria are susceptible to this antibiotic. Otherwise, if the response keeps similar despite the incubation with the antibiotic, the bacteria are not susceptible or resistant to this antibiotic. These responses could be determined at the DNA lev-el, cell wall level, morphological level or any other experimental approach, including metabolic, bio-chemical, physiological or genetic processes.

专利号:JP-H09506857-A
优先权日:1993-07-16
标 题:Synthesis of combinatorial arrays of organic compounds by multi-component combinatorial array synthesis

专利号:EP-0708751-A1
优先权日:1993-07-16
标题:Synthesis of combinatorial arrays of organic compounds through the use of multiple component combinatorial array syntheses

专利号:CA-2167391-A1
优先权日:1993-07-16
标 题 :Synthesis of combinatorial arrays of organic compounds through the use of multiple component combinatorial array syntheses

专利号:ES-2710679-T3
优先权日:2015-01-21
标 题:Procedure for the rapid determination of bacterial susceptibility to antibiotics that inhibit the synthesis of proteins