CAS: 102-02-3; Phenylbiguanide
该化合物是一种七环有机化合物,其特征是具有与苯环系统结合的重氮化功能组,其结构包含两个与芳香苯核心直接相连的瓜尼丁功能.与苯基苯核心有关的主要优势包括其独特的结构图示,它不同于较简单的瓜尼丁衍生物.这种具体安排可以影响生物活动和化学反应.它经常被调查在代谢途径中的潜在作用,或作为生物化学研究的类似作用,因为其独特的化学特征与诸如瓜尼丁或美化与结构有关的化合物等其他大亚胺化物不同.它的合成往往涉及针对这一引信环系的具体的多步骤有机反应.
- 英文名称Phenylbiguanide
- 中文名称1-苯基双胍
- 其它别名Phenyl Biguanide; 1-(Diaminomethylidene)-2-Phenylguanidine; Hm
- CAS编号102-02-3
- MFCD编号:MFCD00179077
- EINECS号:202-998-5
- FDA UNII编号:W8PKA3T2I3
- 分子式:C8H11N5分子量:177.21
- 产品CID: 44594
- 产品分类化学试剂 → 有机试剂 → 胍盐
物理性质
MSDS等安全信息
上下游产品
CAS号142-04-1 苯胺盐酸盐 | CAS号103-72-0 异硫氰酸苯酯 | CAS号4484-20-2 benzenesulphoni... | CAS号15989-47-6 1-苯基-3-脒基硫脲 | CAS号110-86-1 吡啶 | CAS号628-13-7 吡啶盐酸盐 | CAS号141-83-3 1-胺甲醯胍 | CAS号106-51-4 苯醌 | CAS号16120-30-2 4-amino-6-anili... | CAS号30355-69-2 1,3,5-TRIAZINE-... | CAS号30359-95-6 2-N-phenyl-6-pr... | CAS号30355-65-8 1,3,5-TRIAZINE-... | CAS号16018-52-3 N-(6-Methyl-4-o... | CAS号50427-04-8 1-(4-amino-6-an... | CAS号16018-49-8 1-(4,6-DIMETHYL... | CAS号102-06-7 二苯胍合成工艺路线路线简述
📜1-苯基-3-脒基硫脲 反应生成1-苯基双胍
参考文献:Bamberger,Chemische Berichte,1880,Vol. 13,P. 1581
标题:Bamberger,Chemische Berichte,1880,Vol. 13,P. 1581
专利信息
专利号:WO-2024213057-A1
优先权日:2023-04-12
标题:Use of combination of lsd1 inhibitor and drug to treat cancer
发明人：LIU HONG; LI JIA; HUANG HE; WANG JIANG; ZHOU YUBO; REN XUELIAN; LI CHUNPU; KAN WEIJUAN; XU ZICHAO; HU XIAOBEI; WU HENGBO; WANG HANLIN; YE YUNFEI; QIU XIAOHUI; SU MINGBO
权利人:SHANGHAI INST MATERIA MEDICA CAS
摘要:A use of a combination of an LSD1 inhibitor and a drug to treat cancer. Specifically, provided is a composition comprising: a tranylcypromine compound and/or a derivative thereof; and a drug selected from a kinase inhibitor, an anti-cancer drug acting upon or affecting the DNA, an antiviral compound, an antihypertension compound, an antidiabetic compound, a JAK-STAT signaling pathway inhibitor, an NF-κB signaling pathway inhibitor, a protein synthesis inhibitor, a 5-hydroxytryptamine receptor agonist, a dystroglycan modulator, a GABA receptor modulator, or a combination thereof. The two active ingredients have a synergistic effect, and the synergistic treatment effect is significantly better than that of the two individually, thereby remarkably improving the cancer treatment effect.
专利号:WO-2024155314-A1
优先权日:2023-01-18
标 题:Improved enzyme-assisted synthesis of chlorhexidine base
发明人：JAIN PRAJAKTA; JAIN RATNESH; KHARE LALIT
权利人:XTTRIUM LABORATORIES INC
摘要:The present disclosure provides a method for preparing chlorhexidine, salts thereof, or hydrates thereof, wherein the method comprises an enzymatic chlorination, a coupling step, or a combination thereof. The disclosure further includes compositions comprising chlorhexidine prepared by the disclosed methods.
专利号:CA-2482705-A1
优先权日:2002-04-17
标题:Use of meglumine for inhibiting 3-deoxyglucosone synthesis in the skin
专利号:CN-113072692-A
优先权日:2021-03-09
标 题 :A kind of preparation method of high dispersity titanium-based catalyst for polyester synthesis
专利号:CA-2482705-C
优先权日:2002-04-17
标题 :Use of meglumine for inhibiting 3-deoxyglucosone synthesis in the skin
专利号:JP-H03122646-A
优先权日:1989-10-05
标 题:Synthesis method of photopolymerizable compound and liquid photosensitive resin composition
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Medicina et Pharmacologia Experimentalis., 16(267), 1967 []
参考文献:10.1007/bf00301132
摘要:Janvier J-, Peyraud-Waïtzenegger M, Soulier P. Mediation of serotonin-induced hyperventilation via 5-HT3-receptor in European eel Anguilla anguilla. Journal of Comparative Physiology B. 1996 Mar;165(8):640–6. doi: 10.1007/bf00301132.
参考文献:10.1152/ajpheart.00708.2000
摘要:Linz P, Veelken R. Serotonin 5-HT3 receptors on mechanosensitive neurons with cardiac afferents. American Journal of Physiology-Heart and Circulatory Physiology. 2002 May 01;282(5):H1828–35. doi: 10.1152/ajpheart.00708.2000.
参考文献:10.1152/ajpregu.00258.2004
摘要:Verberne AJM, Sartor DM. CCK-induced inhibition of presympathetic vasomotor neurons: dependence on subdiaphragmatic vagal afferents and central NMDA receptors in the rat. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2004 Oct;287(4):R809–16. doi: 10.1152/ajpregu.00258.2004.
摘要:Liu SL, Zhang XY, Xu DY. [Expressions of c-fos in different brain regions after microinjection of 5-HT3 receptors agonist in hippocampus]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2003 Sep;19(5):454–5, 458.
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