专利号:US-7301049-B2 优先权日:2001-06-21 标 题:Photolabile esters and their uses 发明人:SERAFINOWSKI PAWEL JERZY; GARLAND PETER BRYAN 权利人:CANCER RES INST 摘要:Compounds which are capable of generating acid on photolysis are disclosed, and the uses of these compounds, especially for deprotecting the termini of nucleic acid molecules or peptides during synthesis of arrays. The compounds described herein may be employed in the detritylation of 5′-O-dimethoxytrityl (DMT) protected nucleotides by photolysing the compounds to generate an acid capable of removing the DMT group allowing oligonucleotide arrays to be synthesised using readily available 5′-O-DMT-nucleoside-3′-O-phosphoramidite monomers conventionally used in solid phase nucleic acid synthesis. A method of avoiding the effects of stray light in projection lithography techniques is also disclosed.
专利号:WO-2012014109-A1 优先权日:2010-07-30 标题:Heterocyclic sulfonamides as inhibitors of transfer rna synthetase for use as antibacterial agents 发明人:DAS BISWAJIT; UPADHYAY DILIP J; PURNAPATRE KEDAR; GHOSH SOMA; KATOCH RITA 权利人:RANBAXY LAB LTD; DAS BISWAJIT; UPADHYAY DILIP J; PURNAPATRE KEDAR; GHOSH SOMA; KATOCH RITA 摘要:The present invention provides aromatic sulphonamides as tRNA synthetase inhibitors and process for their synthesis, pharmaceutical composition and method for treatment. Compounds disclosed can be used as antibacterial agents for the treatment or prevention of conditions caused by or contributed by aerobic and anaerobic Gram-positive pathogens, more particularly against bacterium, for example Staphylococcus, Enterococci and Streptococci . Compounds disclosed are used in particular for the treatment of skin and soft tissue infection, Formula (I).
专利号:RU-2057753-C1 优先权日:1989-07-07 标 题 :Derivatives of imideazoquinazoline showing positive inotropic and lusitropic properties, method of their synthesis, pharmaceutical composition and a method of treatment
专利号:US-12275686-B2 优先权日:2022-02-22 标 题 :NO donor compound, preparation method thereof, pharmaceutical composition comprising same, and use thereof 发明人:GOU SHAOHUA; YANG WANXIANG 权利人:UNIV SOUTHEAST 摘要:Disclosed is NO donor compound and preparation method, pharmaceutical composition, and use. The compound has a structure represented by formula The NO donor compound and the pharmaceutical composition thereof, as hypoxia-activated NO donors, may be prepared as drugs for treating myocardial hypoxic damage disease. The prepared drugs can exert efficacy at both the cellular level and the animal level, and the synthesis method of the compound is simple and easy to operate.
专利号:CN-114685920-B 优先权日:2022-05-13 标 题:A kind of degradable packaging material and its synthesis method
专利号:CN-114685920-A 优先权日:2022-05-13 标题 :A kind of degradable packaging material and its synthesis method
摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 346. 摘要:Dornan, L. M.; Hughes, N. L.; Muldoon, M. J., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 541.