CAS: 6342-56-9; 1,1-Dimethoxypropan-2-One

相似化合物

96503-30-9 42919-42-6 96503-29-6

上下游产品

CAS号67-56-1 甲醇 | CAS号78-98-8 丙酮醛 | CAS号1401816-27-0 N-trimethoxy-N-... | CAS号75-16-1 甲基溴化镁 | CAS号1186-47-6 methylglyoxal h... | CAS号18664-32-9 1,3-二甲氧基丙酮 | CAS号917-54-4 甲基锂 | CAS号96-26-4 1,3-二羟基丙酮 | CAS号56-82-6 DL-甘油醛 | CAS号18218-93-4 2-methoxyprop-2-enal | CAS号110918-95-1 2-(1,1-dimethox... | CAS号60705-25-1 4,4-二甲氧基乙酰乙酸甲酯 | CAS号180869-36-7 4-(二甲氧甲基)-2-甲硫基嘧啶 | CAS号193747-11-4 4-二甲氧基甲基-2-丙基磺酰基嘧啶 | CAS号180869-38-9 2-甲基氨基嘧啶-4-羧醛二甲基乙缩醛 | CAS号78-98-8 丙酮醛 | CAS号42919-42-6 1,1-二甲氧基丙-2-醇 | CAS号4358-87-6 DL-扁桃酸甲酯 | CAS号21210-43-5 (S)-(+)-扁桃酸甲酯 | CAS号20698-91-3 D-(-)-扁桃酸甲酯

1,3-二甲氧基乙酮置于对甲苯磺酸体系中,用 苯 作为反应溶剂,化学反应 24.0H,以62%的收率获得产物1,1-二甲氧基丙酮
参考文献:Yu,Yin; Chen,Guo-Qiang; Zhu,Jun,Journal Of The Chemical Society. Perkin Transactions I,1990,# 8,P. 2239-2243
标题:Yu,Yin; Chen,Guo-Qiang; Zhu,Jun,Journal Of The Chemical Society. Perkin Transactions I,1990,# 8,P. 2239-2243

专利信息

专利号:WO-2025053792-A1
优先权日:2023-09-06
标题:Collective synthesis of phantomolin family through total synthesis of the sesquiterpene lactone molephantin
发明人：CHIBA SHUNSUKE; PATOURET REMI HENRI LOUIS; LI HOI YEUNG; LAI SOAK KUAN
权利人:UNIV NANYANG TECH
摘要:Disclosed herein are processes to generate an intermediate in the total synthesis of (+)- molephantin or a derivative thereof, and a total synthesis of (+)-molephantin or a derivative thereof. Also disclosed herein are methods of forming a compound of formula XIV and of forming a compound of formula XV, wherein compound of formula XIV and compound of formula XV are as defined in the description.

专利号:US-7884128-B2
优先权日:2005-10-13
标题:Process for total synthesis of pladienolide B and pladienolide D
发明人：KANADA REGINA MIKIE; ITO DAISUKE; SAKAI TAKASHI; ASAI NAOKI; KOTAKE YOSHIHIKO; NIIJIMA JUN
权利人:EISAI R&D MAN CO LTD
摘要:Process for producing compound of Formula: n nwherein P 2 , P 3 and R 2 are the same as defined below, characterized by comprising reacting a compound represented by Formula (7):n n nwherein P 3 means a protecting group for hydroxy group; and Het means a 1-phenyl-1H-tetrazol-5-yl group, with a compound represented by Formula (8):n n nwherein P 2 means a protecting group for hydroxy group; and R 2 means a phenyl group which may be substituted, in the presence of a base.

专利号:US-9187394-B2
优先权日:2011-12-26
标题:Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde
发明人：LV CHUNLEI; PI SHIQING; CHEN JIANHUI; LU DINGQIANG; OUYANG PINGKAI
权利人:NANJING UNIVERSITY OF TECHNOLOGY; ZHEJIANG MED XINCHANG PHARM
摘要:Provided in the present invention is a method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde. The synthesis method comprises the following steps: (1) adding acetaldehyde diethyl acetal and ethyl-(1-propenyl)-ether under the effect of a catalyst to produce 1,1,3-triethoxy-2-methyl-butane; (2) pyrolysis synthesizing 1,1,3-triethoxy-2-methyl-butane under the catalytic effects of isoquinoline and p-Toluenesulfonic acid to produce 1-methoxy-2-methyl-1,3-butadiene; (3) dissolving 1-methoxy-2-methyl-1,3-butadiene in anhydrous ethanol solvent for synthesis with a phase transfer catalyst, cetyl-trimethyl ammonium bromide, and a chlorinating agent, trichloroisocyanuric acid, to generate 4,4-diethoxy-3-methyl-1-chloro-butene; (4) combining 4,4-diethoxy-3-methyl-1-chloro-butene with a triphenylphosphine salt to produce a phosphonium salt; and (5) condensing the phosphonium salt under the effects of hydrogen peroxide in conjunction with sodium carbonate solution to generate 1,1,8,8-tetramethyl-2,7-dimethyl-2,4,6-octatriene; then hydrolyzing under acidic conditions to synthesize 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde. The present invention has a simple process route, is easy to operate, and has mild conditions, great yield, and great industrial value.

专利号:US-2008021226-A1
优先权日:2005-10-13
标题:Process for total synthesis of pladienolide B and pladienolide D

专利号:US-2010204490-A1
优先权日:2005-10-13
标题 :Process for total synthesis of pladienolide b and pladienolide d

专利号:EP-0122479-A1
优先权日:1983-03-18
标 题:3-Chloro-1,1-dialkoxy-acetones and process for their preparation
发明人：PETERSEN HERMANN DR DIPL-CHEM; DEINHAMMER WOLFGANG DR DIPL-IN
权利人:WACKER CHEMIE GMBH
摘要:The invention relates to 3-chloro-1, 1-dialkoxy-acetones of the formula where R is alkyl radicals having 1 to 5 carbon atoms, which, because of their functional groups, are valuable intermediates, in particular for the synthesis of folic acid derivatives. These compounds can be obtained by reacting mixtures of 3-chloro-1-hydroxyimino-acetone and an alkanol with alkyl nitrites in the presence of an inorganic electron pair acceptor, such as hydrogen chloride, at temperatures in the range from -25 ° C to + 60 ° C and purification of the crude products thus obtained by distillation under reduced pressure. 3-Chloro-1-hydroxyiminoacetone, which was obtained immediately before use by reacting 4-chloroacetoacetic acid with sodium nitrite in aqueous solution and subsequent extraction with an organic solvent, as well as alkanols and alkyl nitrites, each having identical alkyl radicals, can be used as reactants Contain 1 to 5 carbon atoms can be used. The compounds that can be produced in this way are stable at room temperature and can be stored for a long time without any tendency to decompose.