CAS: 626-18-6; 1,3-Benzenedimethanol

上下游产品

CAS号626-19-7 间苯二甲醛 | CAS号1477-55-0 间苯二甲胺 | CAS号1459-93-4 间苯二甲酸二甲酯 | CAS号121-91-5 间苯二甲酸(IPA) | CAS号71190-74-4 m-xylyleneglyco... | CAS号107-31-3 甲酸甲酯 | CAS号626-16-4 间二氯苄 | CAS号52010-98-7 3-(羟甲基)苯甲醛 | CAS号929-59-9 1,8-二氨基-3,6-二氧杂辛烷 | CAS号79-22-1 氯甲酸甲酯 | CAS号34231-22-6 3-(氨甲基)苯甲醇 | CAS号41563-69-3 间二苄硫醇 | CAS号226070-69-5 (3-羟基甲基-苄基)-羧酸叔丁酯 | CAS号626-17-5 间苯二甲腈 | CAS号626-15-3 间二溴苄 | CAS号626-16-4 间二氯苄 | CAS号626-19-7 间苯二甲醛 | CAS号52010-98-7 3-(羟甲基)苯甲醛 | CAS号121-91-5 间苯二甲酸(IPA) | CAS号33891-00-8 N-[[3-(benzamid...

间苯二甲酸置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 作为反应溶剂,以75%的收率获得产物1,3-苯二甲醇
参考文献:反式-1,8,12,13-四恶二螺[4.1.4.2]十三烷的合成-一类新的过氧化物
标题:反式-1,8,12,13-四恶二螺[4.1.4.2]十三烷的合成-一类新的过氧化物
摘要:描述了反式-1,8,12,13-四恶二螺并[4.1.4.2]十三烷的合成,这是一类新的过氧化物骨架,其使用伯奇还原芳族化合物,然后进行臭氧分解和酸催化的环化反应.
DOI:10.1016/j.Tetlet.2005.11.107

专利信息

专利号:US-2004152905-A1
优先权日:2003-01-31
标题:Universal building blocks and support media for synthesis of oligonucleotides and their analogs
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and chemically modified oligonucleotide analogs, are provided. In addition, methods for functionalization of a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2008287407-A1
优先权日:2003-12-10
标题 :Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use
发明人：GARVEY DAVID S; FANG XINQIN; KHANAPURE SUBHASH P; RANATUNGA RAMANI R; WEY SHIOW-JYI
权利人:NITROMED INC
摘要:The invention describes novel nitrosated and/or nitrosylated pyruvate compounds and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or nitrosylated pyruvate compound, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one pyruvate compound and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one pyruvate compound, that is optionally nitrosated and/or nitrosylated, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating diseases resulting from oxidative stress, diabetes, reperfusion injury following ischemia, preservation of tissues, organs, organ parts and/or limbs.

专利号:US-4749742-A
优先权日:1985-07-18
标题 :Solid phase peptide synthesis
发明人：ELMORE DONALD T
权利人:QUEENS S UNIVERSITY OF BELFAST
摘要:A method of solid phase peptide synthesis and a reusable insoluble polymer resin having functional groups of the formula n n Resin--NHRNHCO(CH.sub.2).sub.n OH n n wherein R is an branched or straight chain alkyl or cycloalkyl group having 2 to 20 carbon atoms, an aromatic group, substituted aromatic group, heterocyclic group or substituted heterocyclic group preferably 1,4-dimethylcyclohexane, and n is an integer, preferably 3. Phosphorylation followed by reaction with a diol, preferably 1,4-bis(hydroxymethyl)benzene, affords a substrate upon which peptides may be synthesized by repeated deprotection and coupling with protected amino acids.

专利号:US-9045381-B2
优先权日:2010-10-19
标 题:Ruthenium complexes and their uses in processes for formation and/or hydrogenation of esters, amides and derivatives thereof
发明人：MILSTEIN DAVID; BALARAMAN EKAMBARAM; GUNANATHAN CHIDAMBARAM; GNANAPRAKASAM BOOPATHY; ZHANG JING
权利人:MILSTEIN DAVID; BALARAMAN EKAMBARAM; GUNANATHAN CHIDAMBARAM; GNANAPRAKASAM BOOPATHY; ZHANG JING; YEDA RES & DEV
摘要:The present invention relates to novel Ruthenium catalysts and related borohydride complexes, and the use of such catalysts, inter alia, for (1) hydrogenation of amides (including polyamides) to alcohols and amines; (2) preparing amides from alcohols with amines (including the preparation of polyamides (e.g., polypeptides) by reacting dialcohols and diamines and/or by polymerization of amino alcohols); (3) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones) or polyesters); (4) hydrogenation of organic carbonates (including polycarbonates) to alcohols and hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (5) dehydrogenative coupling of alcohols to esters; (6) hydrogenation of secondary alcohols to ketones; (7) amidation of esters (i.e., synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water to form carboxylic acids; and (10) dehydrogenation of beta-amino alcohols to form pyrazines. The present invention further relates to the novel uses of certain pyridine Ruthenium catalysts.

专利号:US-2014142279-A1
优先权日:2012-09-13
标 题:Method for peptide synthesis
发明人：LALEZARI IRAJ; LALEZARI PARVIZ
权利人:LALEZARI IRAJ; LALEZARI PARVIZ
摘要:A new method based on the synthesis and use of novel N and C protecting agents. The new N-protecting agent, here referred to as V-Phenol, generates V-protected amino acids and can be successfully applied to all conventional peptide bond formations including active esters, N,N′-dicyclohexylcarbodiimide (DCC) or related dehydrating agents mixed anhydride methods, PC13 and related agents. The new C-protecting agent, here referred to as HONE, can be successfully applied to peptide synthesis as an active ester not only in combination with V-protected amino acids but also with other N-protecting agents such as Cbz, Boc, Fmoc, etc.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.