专利号:US-2024229131-A1 优先权日:2022-12-22 标 题 :Transition-metal catalyst compositions and methods for sequencing by synthesis 发明人:MARIANI ANGELICA; BEECH TIMOTHY; FRANCAIS ANTOINE; PANIGRAHI ADYASHA; HATTINGH KATHRYN; CRESSINA ELENA 权利人:ILLUMINA INC 摘要:The present application relates to compositions and methods for sequencing by synthesis. A blocking group of a nucleotide may be removed by a transition metal catalyst, the transition metal catalyst activated by a non-reducing ligand and a reducing agent.
专利号:US-2024247311-A1 优先权日:2022-12-22 标题 :Palladium catalyst compositions and methods for sequencing by synthesis 发明人:PEDROSO CASSIO; PANIGRAHI ADYASHA; MARIANI ANGELICA; CARVER ADAM; HOURS RAPHAËLLE; CHANDRACHUD PREETI; FRANCAIS ANTOINE; APSUNDE TUSHAR; HATTINGH KATHRYN; BEECH TIMOTHY; SOLIS DANIEL; LAWRENCE ELLIOT J 权利人:ILLUMINA INC 摘要:The present application relates to palladium catalyst composition and uses in sequencing by synthesis. In particular, the Pd catalyst composition comprises one or more macrocycles (e.g., cyclodextrin or analogs thereof) as additives for improving thermal or oxidative stability of the active Pd(0) species.
专利号:US-2024218443-A1 优先权日:2021-05-20 标 题:Methods of sequencing using 3' blocked nucleotides 发明人:MARIANI ANGELICA; FRANCAIS ANTOINE; TOPPING FREDERICK JAMES; WINNARD CHRISTOPHER; BALDING PHILIP; YUN CHOL STEVEN; IAVICOLI PATRIZIA; HATTINGH KATHRYN; WU XIAOLIN; LIU XIAOHAI 权利人:ILLUMINA INC 摘要:The present application relates to palladium compositions, methods for sequencing by synthesis using nucleotides with 3′ blocking groups, and sequencing kits, where one or more palladium scavengers were used to improve sequencing metrics such phasing and prephasing values.
专利号:CN-105440067-B 优先权日:2016-01-10 标 题 :A kind of technique of 4 borate of synthesis N substituted pyrazolecarboxylics
专利号:CN-113735888-B 优先权日:2021-09-06 标题:A kind of synthesis method of isopropenylboronic acid pinacol ester