CAS: 14686-89-6; 1,2:5,6-Di-O-Isopropylidene-A-D-Gulofuranose

该化合物是核素,甘油和其它复杂的碳水化合物合成的多种中间体;其晶体形式确保高纯度和易处理,使其适合精确的声测应用;硬呋喃环结构还有助于随后的变压,强调其在非合成和制药发展中的效用.

结构式图片

相似化合物

2595-05-3 79943-22-9 16713-80-7

上下游产品

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合成工艺路线路线简述

    双丙酮葡萄糖置于ruthenium Trichloride,Sodium Tetrahydroborate,Potassium Metaperiodate,Celite,Ammonium Chloride,Potassium Carbonate体系中,化学反应生成二丙酮-D-葡萄糖
    参考文献:(-)-Litsenolides C-1和c-2的总合成
    标题:(-)-Litsenolides C-1和c-2的总合成
    摘要:描述了由d-葡萄糖以12%的总收率合成(-)-Litsenolides C 1和c 2的方法,其中α-亚烷基双键是通过c-2含碳水合物衍生物的wittig反应形成的.
    Doi:10.1039/p19870002681

    海关参考信息

    专利信息


    专利号:US-2023137160-A1
    优先权日:2020-03-31
    标 题 :Large scale process for preparing 1,2,4, 6-tetra-o-acetyl-3-azido-3-deoxy-d-galactopyranoside
    发明人:NILSSON ULF; CUMMINS JONATHAN
    权利人:GALECTO BIOTECH AB
    摘要:A process for preparing a compound of formula (X) n n n n n n n n n n The process includes reacting a compound of formula (IX) n n n n n n n n n n with an acetylating agent in the presence of a base in a suitable solvent and at a suitable temperature for a sufficient reaction time for preparing the compound of formula X. The process is suitable for large scale synthesis.

    专利号:US-8846910-B2
    优先权日:2006-08-22
    标题:Matrix metalloproteinase inhibitors
    发明人:SATTIGERI VISWAJANANI J; PALLE VENKATA P; KHERA MANOJ KUMAR; REDDY RANADHEER; TIWARI MANOJ KUMAR; SONI AJAY; RAUF ABDUL REHMAN ABDUL; JOSEPH SONY; MUSIB ARPITA; DASTIDAR SUNANDA G; SRIVASTAVA PUNIT KUMAR
    权利人:RANBAXY LAB LTD
    摘要:The present invention relates to β-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase.
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    主要参考文献

    参考标题:The Rapid Synthesis Of Deoxyfluoro Sugars Using Tris(Dimethylamino)Sulfonium Difluorotrimethylsilicate (Tasf)
    作者:Bogdan Doboszewski,George W. Hay,Walter A. Szarek |发布日期:1987.2.1
    摘要:Deoxyfluoro Sugars Were Synthesized Rapidly By The Reaction Of Trifluoromethanesulfonyl Derivatives Of Partially Protected Sugars With Tris(Dimethylamino)Sulfonium Difluorotrimethylsilicate (Tasf) Under Mild Conditions. The Displacements Occurred With Inversion Of Configuration; Fluorine Has Been Introduced Stereospecifically At Each Of The Secondary Alcoholic Sites Of Aldohexopyranosides And In One

    合成参考文献

    合成方法参考DOI号:10.1016/S0040-4039(98)00241-X
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