CAS: 136705-66-3; (3S,6S)-Octane-3,6-Diol

上下游产品

CAS号10504-06-0 2,5-diethylfuran | CAS号79516-59-9 β-hydroxyvaleri... | CAS号24434-07-9 4-°Ctyne-3,6-diol | CAS号30414-53-0 丙酰乙酸甲酯 | CAS号42558-50-9 (S)-羟基戊酸甲酯 | CAS号136705-64-1 1,2-双((2R,5R)-2...

4-辛炔-3,6-二醇置于platinum On Activated Charcoal,(S)-B-Methyl-4,5,5-Triphenyl-1,3,2-Oxazaborolidine Jones Reagent,Dimethyl Sulfide Borane,氢气体系中,用 四氢呋喃,甲醇 用作溶剂,化学反应生成(3S,6S)-3,6-辛二醇
参考文献:立体选择性还原不饱和的1,4-二酮.制备手性1,4-二醇的实用方法
标题:立体选择性还原不饱和的1,4-二酮.制备手性1,4-二醇的实用方法
摘要:基于硼烷介导的恶唑硼烷催化的2-烯-1,4-二酮(2),2-炔-1,4-二酮(2)还原反应的合成c 2对称手性1,4-二醇的新合成路线描述3)和/或共络二酮4.对二酮3和4的还原分别获得了非常好或优异的对映异构和非对映异构选择性,分别由恶唑硼烷6和5催化.
Doi:10.1016/s0040-4039(96)02476-8

专利信息

专利号:US-7407910-B2
优先权日:2001-10-05
标 题:Ligands for asymmetric reactions
发明人：BERENS ULRICH
权利人:SOLVIAS AG
摘要:The invention relates to a process for the manufacture of bidentate ligands of the formula IA and IIA, characterized in that N,N-(optionally substituted) dialkylamino phosphines bound to an aromatic carbon are lithiated in ortho-position and the lithiated compounds are further converted to said bidentate ligands: n nwherein X 1 is NR, O or S; X 2 is CHR 1 or CR 1 ; X 3 is CHR 2 or NR 2 or, if X 2 is CR 1 , X 3 is CR 2 or N; and R, R 1 and R 2 are radicals such as alkyl groups or R 1 and R 2 together form an annealed ring; Y 1 *, Y 2 * and Y 1 ′* are, independently of each other, an element of the fifth group of the periodic table of elements as such or in thioxo or oxo form; Z 1 *, Z 2 *, Z 3 *, Z 4 *, Z 1 ′*, Z 2 ′* are, independently of each other, for example halogen, hydrogen, or an unsubstituted or substituted moiety selected from radicals such as alkyl groups; the substituents have otherwise the meanings given in the specification; and the ligands are capable of forming metal complexes, which can be used as catalysts in stereoselective synthesis, especially hydrogenation, of various organic molecules.