CAS: 116-26-7; 2,6,6-Trimethylcyclohexa-1,3-Dienecarbaldehyde

相似化合物

23696-85-7 3383-21-9 35044-59-8

上下游产品

1-hydroxymethyl-2,6,6-trimethylcyclohexa-1,3-diene 2,6,6-trimethylcyclohexa-1,3-dienecarbonitrile safranal 2,6,6-trimethylcyclohex-1-enecarbaldehyde2,6,6-trimethyl-cyclohexa-1,3-dienecarbaldehyde-oxime 2,6,6-trimethyl-cyclohexa-1,3-dienecarbaldehyde-thiosemicarbazone 2,6,6-trimethyl-cyclohexa-1,3-dienecarbaldehyde-(2,4-dinitro-phenylhydrazone) (E)-1,1,1-Trifluoro-4-(2,6,6-trimethyl-cyclohexa-1,3-dienyl)-but-3-en-2-one

📜1-Hydroxy-2,2,6-Trimethyl-Cyclohexanecarbonitrile置于吡啶,Sodium Tetrahydroborate,N-溴代丁二酰亚胺(Nbs),氯化亚砜,Cerium(III) Chloride,二异丁基氢化铝,对甲苯磺酸,Calcium Carbonate,过氧化苯甲酰体系中,用 甲醇,四氯化碳,水,甲苯,苯 用作溶剂,化学反应 60.25H,反应生成2,3-二氢-2,2,6-三甲基苯甲醛
参考文献:Kutney,James P.; Gunning,Philip J.; Clewley,Robin G.,Canadian Journal Of Chemistry,1992,Vol. 70,# 7,P. 2094-2114
标题:Kutney,James P.; Gunning,Philip J.; Clewley,Robin G.,Canadian Journal Of Chemistry,1992,Vol. 70,# 7,P. 2094-2114

专利信息

专利号:US-8222458-B2
优先权日:2008-06-13
标题 :Process or synthesis of (3S)- and (3R)-3-hydroxy-beta-ionone, and their transformation to zeaxanthin and beta-cryptoxanthin
发明人：KHACHIK FREDERICK; CHANG AN-NI
权利人:KHACHIK FREDERICK; CHANG AN-NI; UNIV MARYLAND
摘要:Disclosed is a process for the synthesis of (3R)-3-hydroxy-β-ionone and its (3S)-enantiomer in high optical purity from commercially available (rac)-α-ionone. The key intermediate for the synthesis of these hydroxyionones is 3-keto-α-ionone ketal that was prepared from (rac)-α-ionone after protection of this ketone as a 1,3-dioxolane. Reduction of 3-keto-α-ionone ketal followed by deprotection, lead to 3-hydroxy-α-ionone that was transformed into (rac)-3-hydrox-β-ionone by base-catalyzed double bond isomerization in 46% overall yield from (rac)-α-ionone. The racemic mixture of these hydroxyionones was then resolved by enzyme-mediated acylation in 96% ee. (3R)-3-Hydroxy-β-ionone and its (3S)-enantiomer were respectively transformed to (3R)-3-hydroxy-(β-ionylideneethyl)triphenylphosphonium chloride [(3R)-C 15 -Wittig salt] and its (3S)-enantiomer [(3S)-C 15 -Wittig salt] according to known procedures. Double Wittig condensation of these Wittig salts with commercial available 2,5- dimethtylocta-2,4,6-triene-1,8-dial provided all 3 stereoisomers of zeaxanthin. Similarly, (3R)-C 15 -Wittig and its (3S)-enantiomer were each coupled with β-apo-12′-carotenal.

专利号:WO-2020158831-A1
优先权日:2019-01-30
标 题:Transdermal absorption composition with controlled release of water-soluble hydrochloride
发明人：ONO FUMIYASU; GOTO MASAHIRO
权利人:UNIV KYUSHU NAT UNIV CORP; NISSAN CHEMICAL CORP
摘要:The objective of the present invention is to provide a method for simply raising the transdermal absorption properties of a water-soluble hydrochloride without forming a prodrug by organic synthesis.　The present invention relates to: a composition containing a water-soluble hydrochloride and a liposoluble compound having an aldehyde group; a transdermal absorption composition containing said composition, a transdermal absorption control agent, and a liposoluble medium; and a method for controlling the release of the water-soluble hydrochloride from the composition into the skin.

专利号:US-2009311761-A1
优先权日:2008-06-13
标题 :Process for Synthesis of (3S)- and (3R)-3-Hydroxy-Beta-Ionone, and Their Transformation to Zeaxanthin and Beta-Cryptoxanthin

专利号:WO-2016016789-A1
优先权日:2014-07-29
标 题:Aromatic compositions and methods for their production
发明人：EYAL AHARON
权利人:EYAL RES CONSULTANTS LTD
摘要:Disclosed are aroma compositions comprising a key plant aroma compound, plant aroma co-extracts and a synthesis co-product. Also disclosed are methods for the production of such aroma composition and products comprising them.