3-甲基吡啶置于硫酸 双氧水,硝酸体系中,用 溶剂黄146 用作溶剂,化学反应 2.0H,反应生成3-甲基-4-硝基吡啶-N-氧化物 参考文献: Heterocyclic Compounds As Protein Kinase Inhibitors[fr] Composés Hétérocycliques En Tant Qu'Inhibiteurs De Protéine Kinase 标题: Heterocyclic Compounds As Protein Kinase Inhibitors[fr] Composés Hétérocycliques En Tant Qu'Inhibiteurs De Protéine Kinase 摘要:本发明提供了一种异环化合物的化学式(I),其药学上可接受的盐,其前药或水合物,其中a,A',B,D,R1,R2和r3如本文所定义,包括一种化合物的药物组合物的化学式(I)作为活性成分,生产方法和使用方法.特别是,本发明提供了一种化合物的化学式(I),用于治疗或预防与蛋白激酶相关的疾病,症状或紊乱,优选为janus激酶家族.
专利信息
专利号:US-6376655-B1 优先权日:1995-06-02 标题:Physically functional materials 发明人:BERG ROLF HENRIK; HVILSTED SOEREN; RAMANUJAM P S 权利人:RISO NAT LAB 摘要:The invention relates to novel monodisperse or polydisperse compounds, in general named DNO (diamino acid Nα-substituted oligopeptides), preferably low molecular weight polypeptides, e.g., based on ornithine, lysine, diaminobutyric acid, diaminopropionic acid, aminoethylglycine or other amino acids or peptides having azobenzenes or other physicially functional groups, e.g., photoresponsive groups, as side chains. These compounds may be synthesized using solid phase peptide synthesis techniques. Materials, e.g., thin films, comprising such compounds may be used for optical storage of information (holographic data storage), nonlinear optics (NLO), as photoconductors, photonic band-gap materials, electrically conducting materials, electroluminescent materials, piezo-electric materials, pyroelectric materials, magnetic materials, ferromagnetic materials, ferroelectric materials, photorefractive materials, or materials in which light-induced conformational changes can be produced. Optical anisotropy may reversibly be generated with polarized laser light whereby a hologram is formed. First order diffraction efficiencies of up to around 80% have been obtained.