CAS: 88996-23-0; Borane N,N-Diisopropylethylamine Complex

上下游产品

CAS号121-43-7 硼酸三甲酯 | CAS号7087-68-5 N,N-二异丙基乙胺 | CAS号19287-45-7 乙硼烷

Lithium;Hydride,N,N-二异丙基乙胺,硼酸三甲酯,三氯化铝,,Borane Diisopropylethylamine Complex置于氮,二氯甲烷体系中,用 四氢呋喃 作为反应溶剂,化学反应 4.0H,以to Give The Borane N,N-Diisopropyl Ethyl Amine Complex (0.540 G) In 78.7% Yield的收率获得产物n,N-二异丙基乙胺硼烷络合物
参考文献:Process For The Synthesis And Methanolysis Of Ammonia Borane And Borazine
标题:Process For The Synthesis And Methanolysis Of Ammonia Borane And Borazine
摘要:本发明提供了一种改进的氨硼烷和硼氮杂环的合成和甲醇解的方法.

专利信息

专利号:US-6875866-B2
优先权日:2002-02-21
标题:Process for synthesis of D1 receptor antagonists
发明人：DAHANUKAR VILAS H; ECKERT JEFFREY M; GALA DINESH; LUCAS BRIAN; SCHUMACHER DORIS P; ZAVIALOV ILIA
权利人:SCHERING CORP
摘要:In one embodiment, the present invention describes the synthesis of a compound of formula n n nand intermediates therefor.

专利号:US-9802934-B2
优先权日:2013-10-17
标 题 :Process for the synthesis of (R)-praziquantel
发明人：QIAN MINGXIN
权利人:TONGLI BIOMEDICAL CO LTD
摘要:The present disclosure relates to a process and new intermediates for the synthesis of (R)-praziquantel, which is obtained through four steps in proper order, that is, condensation reaction, reduction reaction, acylation reaction and ring-closing reaction, using (1R)-2-substituted-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid as starting material. Overall, the present disclosure provides a (R)-praziquantel product with higher optical purity through a process route that is more cost effective and environmentally friendly.

专利号:US-2006241298-A1
优先权日:2005-04-21
标 题:Methods for synthesis of dicarbamate compounds and intermediates in the formation thereof
发明人：MORTKO HENRY; HE WEIXUAN; ANDERSEN MARC W; DOTSE ANTHONY K; LI JIE
权利人:MORTKO HENRY; HE WEIXUAN; ANDERSEN MARC W; DOTSE ANTHONY K; LI JIE
摘要:Disclosed is a method of making 2-substituted-2-halo-1,3-propanediols via reduction of corresponding malonate compounds. Also disclosed is a method of making 2-substituted-2-halo-1,3-dicarbamate compounds (such as halo derivatives of felbamate, including fluorofelbamate) via reduction of malonate compounds, followed by carbamoylation. Reduction of the malonate compounds is carried out using an electrophilic hydride reagent.

专利号:US-5670666-A
优先权日:1993-09-27
标题:Process for preparing intermediates for the synthesis of D1 antagonists
发明人：HOU DONALD; DRAPER RICHARD W; LEE GARY M; MAS JANET L
权利人:SCHERING CORP
摘要:Disclosed are a process and intermediates of the formulae ##STR1## wherein X - is halide, BF 4 - , R 3 SO 3 - , wherein R 3 is C 1 -C 6 alkyl, CF 3 , C 1 -C 6 alkylphenyl or phenyl, and Q is a group of the formula ##STR2## wherein R is C 1 -C 6 alkyl; useful for preparing benzazepine intermediates of the formula ##STR3## These benzazepine intermediates are useful for preparing benzazepines having activity as selective D1 receptor antagonists.

专利号:US-9695211-B2
优先权日:2008-12-02
标题 :Method for the synthesis of phosphorus atom modified nucleic acids
发明人：WADA TAKESHI; SHIMIZU MAMORU
权利人:WAVE LIFE SCIENCES JAPAN INC
摘要:Described herein are methods of syntheses of phosphorous atom-modified nucleic acids comprising chiral X-phosphonate moieties. The methods described herein provide backbone-modified nucleic acids in high diasteteomeric purity via an asymmetric reaction of an achiral molecule comprising a chemically stable H-phosphonate moiety with a nucleoside/nucleotide.

专利号:US-6462184-B2
优先权日:1999-02-12
标 题:Compounds, processes and intermediates for synthesis of mixed backbone oligomeric compounds
发明人：MANOHARAN MUTHIAH; MAIER MARTIN A
权利人:ISIS PHARMACEUTICALS INC
摘要:Synthetic processes are provided wherein mixed backbone oligomeric compounds are prepared having at least one phosphodiester internucleoside linkage in addition to one or more phosphorothioate, phosphoramidate and boranophosphate internucleoside linkages. Novel H-phosphonate intermediates are also disclosed that are useful in the synthetic processes. The synthetic processes use a novel oxidation step to oxidize H-phosphonate internucleoside linkages to phosphodiester internucleoside linkages without degradation of adjacent phosphorothioate, phosphoramidate and boranophosphate internucleoside linkages. Also provided are synthetic intermediates useful in such processes.