CAS: 821-38-5; Tetradecanedioic Acid

该化合物是一种长链双色箱酸,具有线性14碳主干,在聚合物和特殊化学应用方面有着独特的优势.其扩展的液态结构在多凝聚反应中提高了热稳定性和灵活性,使之适合高性能聚酯,聚氨酯和润滑油.该化合物的双功能碳箱基组使得涂层和粘合物能够精确地交叉连接,提高了耐久性.此外,其纯度和稳定的熔点(125-128°C)确保了精细化学合成的可靠性能.作为基于生物的中间体(来自可再生来源) , 它与可持续物质开发相匹配. 它在水中的低溶解度有利于有机阶段的简单处理.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

1,4-dibromo-butane 1,12-diiodododecane potassium cyanide pentadec-14-enoic aciddimethyl tetradecanedioate diethyl tetradecanedioate 1,14-tetradecanediol hydrogen 14β,16β-O-(4-methoxybenzylidene)card-20(22)-enolide-3β-yl 1,12-dodecanedicarboxylate

合成工艺路线路线简述

  • 合成目标产物 Tetradecanedioic Acid 主要起始原料 2,2':5',2''-Terthiophene
  • 629-59-4 = 821-38-5 [标题:Reaction Conditions
    标题:Acids With Straight And Long Carbon Chains By Using Microorganisms
    参考文献:Federal Republic Of Germany]

    81393-28-4 = 821-38-5
    反应条件:1.1 Reagents: Hydrochloric Acid
    标题:A Malonic Ester Synthesis With Acid Chlorides. The Homologation Of Dioic Acids
    作者:Obaza,Judy; Et Al
    参考文献:Synthetic Communications 日期:1982 卷标:12(1) 页码:19-23]

    57-57-8 + 45037-87-4 = 821-38-5
    反应条件:1.1 Reagents: Cuprate(2-),Tetrachloro-,Lithium (1:2),(Sp-4-1)- Solvents: Tetrahydrofuran
    标题:Organocopper Reagents: Substitution,Conjugate Addition,Carbo/metallocupration,And Other Reactions
    作者:Lipshutz,Bruce H.; Et Al
    参考文献:Organic Reactions (Hoboken 日期:1992 卷标:41]

    68025-28-5 = 821-38-5 [标题:Reaction Conditions
    标题:Synthesis Of Some Long-Chain Primary Alcohols And Related Compounds
    作者:Jones,Reuben G.
    参考文献:Journal Of The American Chemical Society 日期:1947 卷标:69 页码:2350-4]

    22104-81-0 = 821-38-5
    反应条件:1.1 Reagents: Water Catalysts: P-Toluenesulfonic Acid,Palladium Chloride,2-[[[2-[[bis(1,1-Dimethylethyl)Phosphino]Methyl]Phenyl]Methyl](1,1-Dimethylethyl... Solvents: Tetrahydrofuran,Water; Rt; 24 H,40 Bar,125 °C
    标题:Direct And Selective Synthesis Of Adipic And Other Dicarboxylic Acids By Palladium-Catalyzed Carbonylation Of Allylic Alcohols
    作者:Yang,Ji; Et Al
    参考文献:Angewandte Chemie 日期:2020 卷标:59(46) 页码:20394-20398]

    = 821-38-5
    反应条件:1.1 Reagents: Hydrazine Hydrate (1:1) Solvents: Triethanolamine
    标题:Docosanedioic Acid
    作者:Huenig,S.; Et Al
    参考文献:Organic Syntheses 日期:1963 卷标:43 页码:34-40]

    629-73-2 = 821-38-5 [标题:Reaction Conditions
    标题:Microbiological Oxidation Of Long-Chain Aliphatic Compounds. I. Alkanes And 1-Alkenes
    作者:Jones,Derrick F.; Et Al
    参考文献:Journal Of The Chemical Society [section] C: Organic 日期:1968 卷标:(22) 页码:2801-8]

    = 821-38-5
    反应条件:1.1 Reagents: Sodium Cyanoborohydride2.1 Reagents: Hydrochloric Acid
    标题:A Malonic Ester Synthesis With Acid Chlorides. The Homologation Of Dioic Acids
    作者:Obaza,Judy; Et Al
    参考文献:Synthetic Communications 日期:1982 卷标:12(1) 页码:19-23
13-Cyclopent-2-Enyl-Tridecanoic Acid置于permanganate(Vii) Ion体系中,化学反应生成 十四烷二酸
参考文献:Barrowcliff; Power,Journal Of The Chemical Society,1907,Vol. 91,P. 575
标题:Barrowcliff; Power,Journal Of The Chemical Society,1907,Vol. 91,P. 575

海关参考信息

专利信息


专利号:WO-9961509-B1
优先权日:1998-05-21
标题:Synthesis of semi-crystalline polyphthalamides through reactive extrusion of hexamethylene terephthalamide oligomer with lower melting, semi-crystalline or amorphous polyamides
发明人:LEBOEUF CHRISTIAN; HARBOURNE DAVID ALAN
权利人:LEBOEUF CHRISTIAN; HARBOURNE DAVID ALAN
摘要:This invention relates to the synthesis of semi-crystalline polyphthalamides (i.e. containing monomeric units of terephthalic acid and hexamethylene diamine) through reactive extrusion of hexamethylene terephthalamide oligomer, or the oligomer of another 6T-rich copolymer, with lower melting semi-crystalline or amorphous polyamides. This process is particularly useful since it is centered around the use of stirred autoclaves for the synthesis of the 6T oligomer and the semi-crystalline or amorphous polyamides which are subsequently combined in a twin screw extruder equipped for devolatilization of water of reaction. It can also be used for the modification of existing semi-crystalline or amorphous polyamides (not necessarily phthalamides) with low levels of 6T.

专利号:US-9957355-B2
优先权日:2013-06-12
标 题 :Device and method for synthesis of a polymer under separation of a gaseous substance
发明人:ZHU NING; STAMMER ACHIM; CLAUSS JOACHIM; KORY GAD
权利人:BASF SE
摘要:The invention relates to a device for synthesis of a polymer under separation of a gaseous substance. Said device comprises a reaction chamber ( 1 ), which has a top section ( 11 ), a middle section ( 12 ) and a bottom section ( 13 ), an inlet opening ( 2 ) which is arranged in the middle section ( 12 ), a first outlet opening ( 3 ) which is arranged in the bottom section ( 13 ), a second outlet opening ( 4 ) which is arranged in the top section ( 11 ), a first return opening ( 51 ), which is arranged in the bottom section ( 13 ), a second outlet opening ( 52 ), which is arranged under the top section ( 11 ), a distribution device ( 6 ), which is arranged between the top section ( 11 ) and the middle section ( 12 ), and a removal device ( 7 ) which is arranged to be movable along the top section ( 11 ). The invention further relates to a method for synthesis of a polymer which can be carried out in said device.

专利号:US-2024368099-A1
优先权日:2022-01-18
标 题:Methods for the synthesis of di(hydroxymethyl)tetrahydrofuran and its application in polyesters and polyurethanes
发明人:SPIEGELBERG BRIAN; BRANDT ADRIAN; BECK HORST; KUX ALEXANDER; TIN SERGEY; DE VRIES JOHANNES GERARDUS
权利人:HENKEL AG & CO KGAA
摘要:The present invention relates to the synthesis of di(hydroxymethyl)tetrahydrofuran (DHMTHF) and the preparation of trans-enriched mixtures of DHMTHF. The invention further refers to polyester polyols which are obtained by reaction of cis/trans DHMTHF mixtures with a dicarboxylic acid. The invention further relates to polyurethanes and compositions containing a polyester polyol comprising DHMTHF, in particular to such polyurethane-containing (adhesive) compositions.

专利号:WO-2024208876-A1
优先权日:2023-04-03
标题 :Ductile polyamide with the in situ synthesis of a polyimide phase by reactive extrusion
发明人:CASSAGNAU PHILIPPE; DELAGE KARIM; BOUNOR-LEGARE VÉRONIQUE; MARESTIN CATHERINE; DUBOIS CHARLOTTE; GAROIS NICOLAS
权利人:TOTALENERGIES ONETECH; UNIV CLAUDE BERNARD LYON 1 UCBL; CENTRE NAT RECH SCIENT; UNIV JEAN MONNET SAINT ETIENNE UJM; INSTITUT NAT DES SCIENCES APPLIQUEES DE LYON INSA LYON
摘要:The disclosure relates to a ductile polyamide and to a process to produce a ductile polyamide comprising providing components comprising one or more polyamides, one or more dianhydrides, and one or more diamines; wherein the one or more polyamides are provided at a content of at least 60 wt.% based on the total weight of the components; and wherein the one or more polyamides comprise at least one polyamide having amide groups separated by less than 10 carbon atoms; performing in situ synthesis of a polyimide by reactive extrusion of the components wherein the residence time is less than 10 minutes; and recovering a polyamide-polyimide blend being a ductile polyamide comprising a continuous polyamide phase and a dispersed polyimide phase.

专利号:US-4835247-A
优先权日:1988-08-08
标 题:Process for the synthesis of a copolyester adhesive resin
发明人:WILSON JOHN R; ROUSEK MARIAN M; MASSEY FRED L
权利人:GOODYEAR TIRE & RUBBER
摘要:Isophthalic acid is commonly utilized as a comonomer in the preparation of copolyester resins which are utilized as solution adhesives. Unfortunately, solutions of such resins frequently become hazy due to the presence of cyclic oligomers. This invention is based upon the unexpected discovery that the presence of protonic acids during the synthesis of the copolyester resins containing isophthalic acid utilizing conventional metallic catalysts results in solutions of the resins in organic solvents being virtually haze free. The subject invention more specifically reveals a process for synthesizing a polyethylene terephthalate/isophthalate/azelate copolyester resin which is particularly useful as a solution adhesive resin, comprising reacting ethylene glycol with a diacid component which is comprised of (a) from about 25 to about 45 mole percent terephthalic acid, (b) from about 10 to about 30 to about 55 mole percent azelaic acid based upon the diacid component; in the presence of at least one metallic catalyst selected from the group consisting of antimony compounds, titanium compounds; manganese compounds, and germanium compounds and in the presence of at least one protonic acid having a pKa of less than about 2.5; wherein the amount of metallic catalyst present is within the rang eof about 130 ppm to about 1500 ppm and wherein the amount of protonic acid present is within the range of about 50 ppm to about 500 ppm, with said amounts being based upon the weight of the copolyester resin produced.

专利号:US-4921929-A
优先权日:1988-08-08
标 题:Process for the synthesis of a copolyester adhesive resin
发明人:WILSON JOHN R; ROUSEK MARIAN M; MASSEY FRED L
权利人:GOODYEAR TIRE & RUBBER
摘要:Isophthalic acid is commonly utilized as a comonomer in the preparation of copolyester resins which are utilized as solution adhesives. Unfortunately, solutions of such resins frequently become hazy due to the presence of cyclic oligomers. This invention is based upon the unexpected discovery that the presence of protonic acids during the synthesis of the copolyester resins containing isophthalic acid utilizing conventional metallic catalysts results in solutions of the resins in organic solvents being virtually haze free. The subject invention more specifically reveals a process for synthesizing a polyethylene terephthalate/isophthalate/azelate copolyester resin which is particularly useful as a solution adhesive resin, comprising reacting ethylene glycol with a diacid component which is comprised of (a) from about 25 to about 45 mole percent terephthalic acid, (b) from about 10 to about 30 mole percent isophthalic acid, and (c) from about 30 to about 55 mole percent azelaic acid based upon the diacid component; in the presence of at least one metallic catalyst selected from the group consisting of antimony compounds, titanium compounds; manganese compounds, and germanium compounds and in the presence of at least one protonic acid having a pKa of less than about 2.5; wherein the amount of metallic catalyst present is within the range of about 130 ppm to about 1500 ppm and wherein the amount of protonic acid present is within the range of about 50 ppm to about 500 ppm, with said amounts being based upon the weight of the copolyester resin produced.
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合成参考文献


摘要:Nolte, J. C.; Urlacher, V. B., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 39.
参考文献:10.1007/s11745-015-4077-x
摘要:Santalova EA, Denisenko VA, Dmitrenok PS. Structural Analysis of the Minor Cerebrosides from a Glass Sponge Aulosaccus sp. Lipids. 2015 Dec;50(12):1209–18. doi: 10.1007/s11745-015-4077-x.
参考文献:10.1007/s00726-017-2391-8
摘要:Engskog MKR, Ersson L, Haglöf J, Arvidsson T, Pettersson C, Brittebo E. β-N-Methylamino-l-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling. Amino Acids. 2017 Feb 04;49(5):905–19. doi: 10.1007/s00726-017-2391-8.
参考文献:10.1186/s13568-018-0605-4
摘要:Sugiharto YEC, Lee H, Fitriana AD, Lee H, Jeon W, Park K, Ahn J, Lee H. Effect of decanoic acid and 10-hydroxydecanoic acid on the biotransformation of methyl decanoate to sebacic acid. AMB Express. 2018 May 05;8(1):75.
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