CAS: 76-65-3; Amolanone
该化合物是独特的结构,包括一个纳入环状框架的氮原子,该化合物一般无色至青黄,有独特的气味.阿莫拉诺酮以其在有机溶剂中的溶解性而著称,在各种化学应用中有用.在标准条件下,它具有中等稳定性,但可能会发生典型的阿米因反应,如核脑嗜血替代.在安全方面,必须谨慎处理阿莫拉农酮,因为若吸入或摄入,可能会对健康造成危害,而且应当采取适当的安全措施避免接触.其应用范围包括制药用途和有机合成的中间体.与任何化学物质一样,了解其特性和处理要求对于实验室和工业环境中的安全有效使用至关重要.
- 英文名称Amolanone
- 中文名称阿莫拉酮
- IUPAC名称2(3H)-Benzofuranone, 3-(beta-diethylaminoethyl)-3-phenyl-
- 其它别名Butyricacid, 4-diethylamino-2-(o-hydroxyphenyl)-2-phenyl-, g-lactone (6CI); 3-(2-Diethylaminoethyl)-3-phenyl-2(3H)-benzofuranone; 3-(b-Diethylaminoethyl)-3-phenyl-2-benzofuranone; AP 43; Amethone; Amolanon; Amolanone
- CAS编号76-65-3
- MFCD编号:MFCD00864450
- FDA UNII编号:1ALL724WB1
- 分子式:C20H23NO2分子量:309.407
- 产品CID: 1758998
- 产品分类有机原料 → 有机杂环化合物 → 香豆素
物理性质
MSDS等安全信息
上下游产品
3-苯基-3H-1-苯并呋喃-2-酮 3-Phenyl-3H-Benzofuran-2-One 3117-37-1合成工艺路线路线简述
📜3-苯基-3H-1-苯并呋喃-2-酮,N,N-二乙基氯乙胺 反应生成 阿莫拉酮
参考文献:Antispasmodics. Derivatives Of 3-Phenyl-2-Benzofuranone1
标题:Antispasmodics. Derivatives Of 3-Phenyl-2-Benzofuranone1
摘要:
DOI:10.1021/ja01123A021
海关参考信息
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2902700000-异丙基苯
2905121000-正丙醇
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专利信息
专利号:US-7993390-B2
优先权日:2002-02-08
标 题:Implantable or insertable medical device resistant to microbial growth and biofilm formation
发明人：MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN
权利人:BOSTON SCIENT SCIMED INC
摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Hjuler CT, Maolanon NN, Sauer J, Stougaard J, Thygesen MB, Jensen KJ. Preparation of glycoconjugates from unprotected carbohydrates for protein-binding studies. Nat Protoc. 2017 Nov;12(11):2411-2422. doi: 10.1038/nprot.2017.109. Epub 2017 Oct 26. doi: 10.1021/acs.biochem.7b00725. Epub 2017 Sep 15. doi: 10.1021/acschemneuro.7b00117. Epub 2017 May 30.
4: Maolanon AR, Kristensen HM, Leman LJ, Ghadiri MR, Olsen CA. Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes. Chembiochem. 2017 Jan 3;18(1):5-49. doi: 10.1002/cbic.201600519. Epub 2016 Dec 8. Review. doi: 10.1016/j.chembiol.2016.06.011. Review. doi: 10.1021/jm501399d. Epub 2014 Nov 7. doi: 10.1002/cbic.201402125. Epub 2014 Aug 26. doi: 10.1002/cbic.201300520. Epub 2014 Jan 16. doi: 10.1021/jm4008449. Epub 2013 Aug 5. Erratum in: J Med Chem. 2013 Sep 12;56(17):7135. doi: 10.1073/pnas.1205171109. Epub 2012 Aug 2.
11: Frandsen RJ, Nielsen NJ, Maolanon N, Sørensen JC, Olsson S, Nielsen J, Giese H. The biosynthetic pathway for aurofusarin in Fusarium graminearum reveals a close link between the naphthoquinones and naphthopyrones. Mol Microbiol. 2006 Aug;61(4):1069-80.
合成参考文献
摘要:Journal of Urology., 54(75), 1945
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