CAS: 57396-78-8; 5,6-Dihydroxy-2-Phenyl-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One
该化合物是一种来自Baicalein的裂变胶质,它是各种植物,特别是Scutellaria baicenses的根部的化合物,其化学结构特征是其化学结构,包括一个flavoone脊椎,附着7点的葡萄糖.它展示了一系列生物活动,包括抗氧化剂,抗炎和潜在的抗癌特性,因此对药理学研究感兴趣.Baicalein-7-O-glucoside在水和有机溶剂中可溶解,这增加了其生物利用率.其稳定性可能受到诸如pH和温度等因素的影响.该化合物经常被研究其在各种疾病中的治疗潜力,包括心血管和...
- 英文名称5,6-Dihydroxy-2-Phenyl-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One
- 中文名称千层纸苷A
- IUPAC名称5,6-dihydroxy-2-phenyl-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
- 其它别名BAICALEIN 7-O-B-D-GLUCOPYRANOSIDE (BAICALIN); 5,6-Dihydroxy-7-(β-D-glucopyranosyloxy)-2-phenyl-4H-1-benzopyran-4-one; 5,6-Dihydroxy-7-(β-D-glucopyranosyloxy)flavone; 5,6-Dihydroxyflavone-7-yl β-D-glucopyranoside; 7-(β-D-Glucopyranosyloxy)-5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one; 7-(β-D-Glucopyranosyloxy)-5,6-dihydroxyflavone; Baicaleine-7-glucoside; Baicalein-7-O-glucoside
- CAS编号57396-78-8
- MFCD编号:MFCD22125001
- EINECS号:110-082-0
- 分子式:C21H20O10分子量:432.38
- 产品CID: 1548942
- 产品分类生物化工 → 提取物 → 植物提取物
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号67047-05-6 4-oxo-2-phenyl-... | CAS号67047-06-7 7-(benzyloxy)-4... | CAS号74293-55-3 5,6-Diacetoxy-7... | CAS号572-09-8 2,3,4,6-四乙酰氧基-a... | CAS号67047-07-8 5,6-Diacetoxy-7... | CAS号491-67-8 黄芩素； 黄芩苷元合成工艺路线路线简述
📜黄芩苷置于sodium Tetrahydroborate,硫酸体系中,化学反应 3.0H,反应生成 千层纸苷a
参考文献:A Convenient And Efficient Approach To Synthesize Negletein From Baicalin
标题:A Convenient And Efficient Approach To Synthesize Negletein From Baicalin
摘要:A Simple Two-Step/one-Pot And Highly Efficient Strategy For The Synthesis Of Negletein From Naturally Abundant And Inexpensive Baicalin Has Been Developed. In This One-Pot Sequence,Esterification Of Baicalin Catalyzed By Concentrated H2So4 In Methanol Followed By The Treatment With Excess Nabh4 Afforded Negletein In Moderate Yield. This Method Provides An Additional Approach For The Synthesis Of Negletein. (C) 2016 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tetlet.2016.03.085
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10407401-B1
优先权日:2018-08-04
标题 :Process for synthesis of Oroxylin A
发明人：MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA; SAMI LABS LTD
摘要:Disclosed is a novel, simple, scalable and environment friendly process for the synthesis of Oroxylin A from Baicalin. Baicalin is esterified to obtain a methyl ester which is further selectively methylated to provide Oroxylin A glucuronide methyl ester which on de-glycosylation results in the formation of Oroxylin A.
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合成参考文献
参考文献:10.1093/chromsci/bmz054
摘要:Yin XS, Zhang XQ, Yin JT, Kong DZ, Li DQ. Screening and identification of potential tyrosinase inhibitors from Semen Oroxyli extract by ultrafiltration LC-MS and in silico molecular docking. J Chromatogr Sci. 2019 Oct 17;57(9):838–46. doi: 10.1093/chromsci/bmz054.
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