CAS: 55712-37-3; 2,4,3'-Trichlorobiphenyl
该化合物是一种该化合物是一种合成有机化学品,主要用于研究和工业应用,特别是用作环境和分析化学的参考标准;它具有稳定性和持久性,有助于研究环境基质中的多氯联苯行为;它有明确界定的结构,能够精确校准气体色谱学和质谱学分析;由于它的氯化模式,它成为调查多氯联苯降解途径和毒理学影响的示范化合物;适当的处理是必要的,因为它由于环境持久性和潜在的生物累积性,它属于管制管制范围.
- 英文名称2,4,3'-Trichlorobiphenyl
- 中文名称2,3',4-三氯联苯
- IUPAC名称2,4-dichloro-1-(3-chlorophenyl)benzene
- 其它别名2,3',4-Trichlorobiphenyl; 2,4,3'-Trichlorobiphenyl; 2',3,4'-Trichlorobiphenyl; 3,2',4'-Trichlorobiphenyl; PCB 25
- CAS编号55712-37-3
- FDA UNII编号:7R1YUR0FC9
- 分子式:C12H7Cl3分子量:257.547
- 产品CID: 1528544
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
合成工艺路线路线简述
📜三甲基(2,6-二氯苯基)硅置于四丁基氟化铵,仲丁基锂体系中,用 四氢呋喃,环己烷,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 25.5H,反应生成 2,3',4-三氯联苯
参考文献:间位而非邻位定向金属化:支撑效应妨碍从(2,6-二卤苯基)硅烷中提取质子
标题:间位而非邻位定向金属化:支撑效应妨碍从(2,6-二卤苯基)硅烷中提取质子
摘要:(2,6-二氯苯基)三甲基-和-三乙基硅烷对强碱表现出非典型的反应模式.当用 2,2,6,6-四甲基哌啶锂在-100 摄氏度下处理时,它们会产生两种,仲丁基或叔丁基锂,甚至三种不同的有机金属中间体,它们可以被标准物质截获.亲电试剂.三烷基甲硅烷基在两个方面介入.对相邻的氯原子施加空间压力,它促进其中一个原子对锂的置换置换,这是一种副反应,每当烷基锂化合物时就会发生.受雇.同时,由于空间位阻的中继传输,它阻止了紧邻卤素的碱对氢原子的攻击.作为结果,去质子化优先或仅发生在 5-(Qmetaq) 而不是 4-(Qorthoq) 位置.4-锂化物种,作为副产品或 Sep 产生.通过置换卤素/金属互变,在-75 摄氏度下消除氯化锂以释放被芳基锂前体捕获的二脱氢苯 (Qarynesq).[在 Scifinder (R) 上]
DOI:10.1002/ejoc.200500553
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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