CAS: 408324-00-5; 3,5-Dihydroxy-1-(3,4-Dihydroxyphenyl)-7-(4-Hydroxyphenyl)Heptane

该化合物是一种多酚化合物,其特点是具有立体特定氢氧化模式和扩展的七苯基,其结构特征,包括芳香环和顺流链上的多羟基化合物,有助于其作为抗氧化剂和生物活性中间体的潜力.(3R,5R)配置确保立体化学精度,这可能会增强生物系统中的结合性.由于该化合物在结构上与类和其他苯丙胺代谢物相似,因此对医药化学和天然产品研究具有兴趣.其定义明确的立体化学和多功能性质使其适合针对氧化性应力调制或衍生合成的支撑剂的研究.

英文名称3,5-Dihydroxy-1-(3,4-Dihydroxyphenyl)-7-(4-Hydroxyphenyl)Heptane
中文名称4-[(3R,5R)-3,5-二羟基-7-(4-羟基苯基)庚基]-1,2-苯二酚
IUPAC名称4-((3R,5R)-3,5-dihydroxy-7-(4-hydroxyphenyl)heptyl)benzene-1,2-diol
其它别名3,5-Dihydroxy-1-(3,4-Dihydroxyphenyl) -7-(4-Hydroxyphenyl)Heptane; 4-[(3R,5R)-3,5-Dihydroxy-7-(4-Hydroxyphenyl)Heptyl]-1,2-Benzenediol; 1,2-Benzenediol, 4-[(3R,5R)-3,5-Dihydroxy-7-(4-Hydroxyphenyl)Heptyl]-
CAS编号408324-00-5
MFCD编号:MFCD27969062
分子式:C19H24O5分子量:332.4
产品CID: 1422382
产品分类天然产物 → 酚类

相似结构搜索
InChIKey: XLTITIJKWVRJMS-IAGOWNOFSA-N
InChI=1S/C19H24O5/c20-15-6-1-13(2-7-15)3-8-16(21)12-17(22)9-4-14-5-10-18(23)19(24)11-14/h1-2,5-7,10-11,16-17,20-24H,3-4,8-9,12H2/t16-,17-/m1/s1
计算化学: 氢键受体数5.0氢键供体数5.0可旋转键数8.0

MSDS等安全信息

警示词Warning
危险描述H315-H319-H335-
防范说明P261-P305+P351+P338-
安全声明H303+H313+H333

上下游产品

(3R,5R)-3,5-diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane (3R,5R)-1-(3,4-Dimethoxy-phenyl)-7-(4-methoxy-phenyl)-heptane-3,5-diol

合成工艺路线路线简述

📜(3R,5R)-3,5-Diacetoxy-1-(3,4-Dihydroxyphenyl)-7-(4-Hydroxyphenyl)Heptane置于盐酸体系中,用甲醇作为反应溶剂,化学反应生成 4-[(3R,5R)-3,5-二羟基-7-(4-羟基苯基)庚基]-1,2-苯二酚
参考文献:Diarylheptanoids From Curcuma Kwangsiensis And Their Inhibitory Activity On Nitric Oxide Production In Lipopolysaccharide-Activated Macrophages
标题:Diarylheptanoids From Curcuma Kwangsiensis And Their Inhibitory Activity On Nitric Oxide Production In Lipopolysaccharide-Activated Macrophages
摘要:Eleven Diarylheptanoids (1-11) Were Isolated From Rhizomes Of Curcuma Kwangsiensis,Together With Seven Known Compounds. Their Structures Were Elucidated By 1D And 2D NMR,Circular Dichroism (Cd),And Accurate Mass Measurements. Inhibitory Effects Of The Isolated Compounds On Nitric Oxide Production In Lipopolysaccaride-Activated Macrophages Were Evaluated. Compounds 1,2,And 3 Showed Strong Inhibitory Activity On No Production With Ic50 Values Of 3.13,2.81 And 2.41 Mu M,Respectively. (C) 2011 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2011.07.012