CAS: 39621-00-6; 2,6-Dichloro-4-Methylpyridine

相似化合物

3678-62-4 32710-65-9 113293-70-2

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CAS号2402-78-0 2,6-二氯吡啶 | CAS号74-88-4 碘甲烷 | CAS号98027-84-0 2,6-二氯-4-碘吡啶 | CAS号823-96-1 三甲基环三硼氧烷 | CAS号52313-61-8 2-氯-4-甲基吡啶-N-氧化物 | CAS号824-72-6 苯膦酰二氯 | CAS号4664-16-8 2,6-二羟基-4-甲基吡啶 | CAS号51564-92-2 2-氨基-6-氯-4-甲基吡啶

2-氯-4-甲基吡啶置于间氯过氧苯甲酸,三氯氧磷体系中,用 二氯甲烷,甲苯 用作溶剂,化学反应 28.0H,反应生成2,6-二氯-4-甲基吡啶
参考文献: Antiviral Compounds[fr] Composés Antiviraux
标题: Antiviral Compounds[fr] Composés Antiviraux
摘要:本文披露了新的抗病毒化合物,以及包括一种或多种抗病毒化合物的药物组合物,以及合成这些化合物的方法.本文还披露了使用一种或多种小分子化合物改善和/或治疗副粘病毒病毒感染的方法.副粘病毒感染的例子包括由人类呼吸道合胞病毒(rsv)引起的感染.

专利信息

专利号:US-7148356-B2
优先权日:2001-07-13
标题:Process for the catalytic synthesis of biaryls and polymers from aryl compounds
发明人：SMITH III MILTON R; MALECZKA ROBERT E
权利人:UNIV MICHIGAN STATE
摘要:A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO 2 CF 3 ), or nonaflate (OSO 2 C 4 F 9 ). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.

专利号:US-12172982-B2
优先权日:2020-08-12
标 题:Synthesis of quinazoline compounds
发明人：LIM NGIAP-KIE; SHEN JEFF; SIROIS LAUREN ELIZABETH; TIMMERMAN JACOB C; TRACHSEL ETIENNE; WHITE NICHOLAS ANDREW; XU JIE; ZHANG HAIMING; BACHMANN STEPHAN; BIGLER RAPHAEL; CLAGG KYLE BRADLEY PASCUAL; DIPASQUALE ANTONIO GIOVANNI; GOSSELIN FRANCIS; ORCEL UGO JONATHAN; MEIER ROLAND CHRISTOPH
权利人:GENENTECH INC; HOFFMANN LA ROCHE
摘要:Provided herein are methods of synthesizing quinazoline compounds comprising at least one atropisomeric center.

专利号:US-2018051042-A1
优先权日:2016-08-22
标题 :Methods for forming saturated (hetero)cyclic borylated hydrocarbons and related compounds
发明人：SMITH III MILTON R; SHANNON TIMOTHY M; MALECZKA JR ROBERT E; FORNWALD RYAN M
权利人:UNIV MICHIGAN STATE
摘要:The disclosure relates to methods for forming at least partially saturated cyclic and heterocyclic borylated hydrocarbons, as well as related compounds, which can be precursor compounds in the synthesis of any of a variety of pharmaceutical or medicinal compounds with a desired structure and/or stereochemistry for drug synthesis or drug candidate evaluation. The methods generally include reduction of an unsaturated cyclic or heterocyclic borylated hydrocarbon having a boron-containing substituent at an sp 2 -carbon, where such reduction converts the sp 2 -carbon to an sp 3 -carbon at the point of attachment of the boron-containing substituent. The methods can exhibit a selectivity for syn-addition during reduction, which can provide stereospecific products, such as when the unsaturated cyclic or heterocyclic reactant is multiply substituted with boron groups and/or other functional groups.

专利号:US-7329769-B2
优先权日:2001-07-13
标 题:Catalytic boronate ester synthesis from boron reagents and hydrocarbons
发明人：SMITH III MILTON R
权利人:UNIV MICHIGAN STATE
摘要:A process for producing a ring-substituted arene borane which comprises reacting a ring-substituted arene with an HB organic compound in the presence of a catalytically effective amount of an iridium or rhodium complex with three or more substituents, excluding hydrogen, bonded to the iridium or rhodium and a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium, to form the ring-substituted arene borane. Also provided are catalytic compounds for catalyzing the process comprising an iridium or rhodium complex with three or substituents, excluding hydrogen, bonded to the iridium or rhodium and optionally, a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium.

专利号:US-2005182261-A1
优先权日:2001-07-13
标 题:Process for the catalytic synthesis of biaryls and polymers from aryl compounds

专利号:WO-2022035790-A1
优先权日:2020-08-12
标题:Synthesis of quinazoline compounds