CAS: 38769-92-5; 4-Methoxybenzylmagnesium Chloride

该化合物是具有分子式C8H9ClMgO的 Grignard试剂. 有机磁共聚物具有高度反应性,是有机合成的多种媒介,特别是碳碳结层的形成,其主要优势包括碳酰化合物的核生殖添加具有高度选择性,与一系列功能组相容. 4-甲基苯基的出现,增强了其在受控制环境中的稳定性和回活动性. 它通常用于制药和精细化学合成,对反应结果提供精确的控制. 在惰性条件下的妥善处理由于其对湿度和空气的敏感度至关重要.

英文名称4-Methoxybenzylmagnesium Chloride
中文名称4-甲氧苄基氯化镁
IUPAC名称magnesium;1-methanidyl-4-methoxybenzene;chloride
其它别名p-Methoxybenzylmagnesium chloride (6CI); Benzene, 1-methoxy-4-methyl-, magnesium complex; 4-Methoxybenzylmagnesium chloride; 4-Methoxyphenylmethylmagnesium chloride; Chloro(4-methoxyphenylmethyl)magnesium
CAS编号38769-92-5
MFCD编号:MFCD01311491
EINECS号:695-992-0
分子式:C8H9ClMgO分子量:180.91
产品CID: 1399796
产品分类有机原料 → 有机金属类化合物 → 有机镁

相似结构搜索
InChIKey: UDWJEJINASVQGJ-UHFFFAOYSA-M
InChI=1S/C8H9O.ClH.Mg/c1-7-3-5-8(9-2)6-4-7;;/h3-6H,1H2,2H3;1H;/q;;+1/p-1
计算化学: 氢键受体数3.0氢键供体数*可旋转键数1.0

MSDS等安全信息

GHS象形图
GHS符号GHS05;
注释: Corrosion
危险类别皮肤腐蚀类别1B
严重眼损伤类别1
警示词Danger(危险)
危险描述H314 |造成严重皮肤灼伤和眼损伤.
H318 |造成严重眼损伤.
防范说明P280a-P303+P361+P353-P305+P351+P338-P501a-P210-P280-P301+P312+P330-P305+P351+P338+P310-P370+P378-P403+P235
危险等级3
UN编号UN 2924 3/PG 2
危险品标志F,C,Xn
安全声明16-26-33-36/37/39-43-45-36/37-60-8
危险类别码11-14/15-19-34-40-36/37-14
WGK Germany1

欧盟法规

ECHA物质C&L通报

上下游产品

合成工艺路线路线简述

合成目标产物 4-Methoxybenzylmagnesium Chloride 主要起始原料 4-Methoxybenzylchloride
(文献来源)合成步骤主要原料 4-Methoxybenzylchloride

海关参考信息

2902300000-甲苯
2905110000-甲醇
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-3093650-A
优先权日:
标题 :Alternative synthesis of

专利号:US-2003225132-A1
优先权日:2002-04-11
标题:Estrogen receptor modulators
发明人：DININNO FRANK P; HAMMOND MILTON LLOYD
摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.

专利号:US-6750213-B2
优先权日:2000-10-19
标题:Estrogen receptor modulators
发明人：DININNO FRANK P; WU JANE Y; KIM SEONGKON; CHEN HELEN Y
权利人:MERCK & CO INC
摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.