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专利信息

专利号:WO-2022238500-A1
优先权日:2021-05-12
标题 :Radiosynthesis of [18f] talazoparib
发明人：BOWDEN GREGORY DAVID; MAURER ANDREAS; STOTZ SOPHIE; KINZLER PAUL JOHANNES OSKAR MARIA; LAEMMERHOFER MICHAEL; ZENDER LARS; PICHLER BERND
权利人:UNIV TUEBINGEN MEDIZINISCHE FAKULTAET
摘要:The present invention relates to the synthesis of Poly (ADP ribose) polymerase (PARP) inhibitors and particularly to the radiosynthesis of PARP 1 inhibitors, more particularly to the synthesis of [18F] talazoparib.

专利号:US-5998595-A
优先权日:1996-11-05
标题:Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups
发明人：KUSUMOTO SHOICHI; FUKASE KOICHI
权利人:WAKO PURE CHEM IND LTD
摘要:Azidohalogenobenzyl derivatives of the formula (I) ##STR1## wherein A is a halogen atom, B is a halogen atom or a hydrogen atom, and X is a group reactive with a hydroxy group, methods of protecting hydroxy group(s) using said derivatives, and sugar compounds wherein a hydrogen atom of at least one hydroxy group is substituted by an azidohalogenobenzyl group. According to the present invention, there are provided novel derivatives capable of introducing a group into a compound having hydroxy group(s), which group is useful as a stable hydroxy-protecting group even in solid phase synthesis for the purpose of the extension of sugar chain under continuous acidic conditions and of being removed under mild conditions; sugar compounds protected by using said derivatives; and methods of protecting hydroxy group(s) using said derivatives.

专利号:US-12404293-B2
优先权日:2019-02-28
标 题 :Method for producing glycan, building block for gylican synthesis, and compound
发明人：NOKAMI TOSHIKI; ITOH TOSHIYUKI; SAKAI HIRAKU; HAMADA TOMOAKI
权利人:NAT UNIV CORP TOTTORI UNIV; KOGANEI LTD
摘要:This invention provides a method for producing a glycan with improved yield ratio of streocontrolled glycan. Additionally it provides the building blocks used as the sugar donor and as the sugar acceptor to implement a method for producing the glycan. It also provides a novel compound. It subjects the specific building block A of this invention to electrolytic oxidation in an aprotic organic solvent that contains an electrolyte; and subjects the specific building block B of this invention to glycosylation with the electrolytically oxidized building block A in the method for producing a glycan based on the liquid phase process.

专利号:US-6632940-B1
优先权日:1998-04-14
标 题 :Method for laminaribiose synthesis
发明人：YVIN JEAN-CLAUDE; JAMOIS FRANK; FERRIERES VINCENT; PLUSQUELLEC DANIEL
权利人:GOEMAR LAB SA
摘要:The invention concerns a method for preparing Laminaribiose comprising a step for glycoside binding between a donor and an acceptor of glycosyl. The invention is characterized in that the glycosyl donor is in pyranose form and corresponds to formula (II); the glycosyl acceptor is in furanose form and corresponds to formula (III); said binding step is performed in solution in an anhydrous organic solvent, at a temperature ranging between -80° C. and 40° C., for a time interval ranging between 1 minute and 8 hours, in the presence of a suitable promoter.

专利号:CN-112409118-A
优先权日:2020-11-20
标 题:A kind of method for electrochemical synthesis of trans-4-(trans-4'-alkylcyclohexyl)cyclohexylene liquid crystal monomer

专利号:FR-2777281-A1
优先权日:1998-04-14
标题 :PROCESS FOR THE SYNTHESIS OF D-LAMINARIBIOSIS