CAS: 2144-37-8; Methyl 5-(Chloromethyl)Furan-2-Carboxylate

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果糖置于jones Reagent,水,Magnesium Chloride体系中,用 乙醚,丙酮,甲苯 用作溶剂,化学反应 1.67H,反应生成5-(氯甲基)-2-糠酸甲酯
参考文献:Novel Peptides Comprising Furanoid Sugar Amino Acids For The Treatment Of Cancer
标题:Novel Peptides Comprising Furanoid Sugar Amino Acids For The Treatment Of Cancer
摘要:描述了包含呋喃糖氨基酸的抗癌肽及使用这些肽制备的组合物.公开了合成这些肽和制备呋喃糖氨基酸的方法.使用这些肽制备的肽和组合物在这些肽特别在治疗和预防癌症和肿瘤方面具有药理应用.

专利信息

专利号:WO-2019170204-A1
优先权日:2018-03-05
标 题 :Synthesis of precursors of 2,5-furandicarboxylic acid
发明人：PEDERSEN MARTIN; PEDERSEN CHRISTIAN
权利人:UNIV COPENHAGEN
摘要:The present invention relates to a method for the manufacture of stable FDCA precursors from saccharide derived starting materials. More specific the invention relates to the synthesis of FDCA precursors such as alkyl 5-(hydroxymethyl)furan-2-carboxylates or 5-(hydroxymethyl)furan-2-carboxylic acid in an expedient, practical and environmental benign manner from e.g. D-glucono-δ-lactone. These bio-based monomer building blocks hold great potential in the manufacture of polymer materials.

专利号:US-2010152208-A1
优先权日:2007-05-23
标 题:Bicyclic heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LEGER SERGE; DESCHENES DENIS; FORTIN REJEAN; ISABEL ELISE; POWELL DAVID
权利人:MERCK FROSST CANADA LTD
摘要:Bicyclic heteroaromatic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; Type 2 diabetes; insulin resistance; hyperglycemia; Metabolic Syndrome; neurological disease; cancer; and liver steatosis. Formula (I).