CAS: 1369767-20-3; ((1S,2R)-1-(3-Fluorophenyl)Cyclopropane-1,2-Diyl)Dimethanol

英文名称((1S,2R)-1-(3-Fluorophenyl)Cyclopropane-1,2-Diyl)Dimethanol
中文名称((1S,2R)-1-(3-氟苯基)环丙烷-1,2-二基)二甲醇
IUPAC名称((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2-diyl)dimethanol
其它别名((1S,2R)-1-(3-Fluorophenyl)Cyclopropane-1,2-Diyl)Dimethanol; 1,2-Cyclopropanedimethanol, 1-(3-Fluorophenyl)-, (1S,2R)-; (1S,2R)-1-(3-Fluorophenyl)-1,2-Cyclopropanedimethanol; (1S,2R)-1-(3-Fluorophenyl)Cyclopropane-1,2-Dimethanol
CAS编号1369767-20-3
MFCD编号:MFCD30803289
EINECS号:857-048-8
分子式:C11H13FO2分子量:196.22
产品CID: 576068
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: LYRQPKNAZSUDKZ-GXSJLCMTSA-N
InChI=1S/C11H13FO2/c12-10-3-1-2-8(4-10)11(7-14)5-9(11)6-13/h1-4,9,13-14H,5-7H2/t9-,11+/m0/s1
计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数3.0

相似化合物

1450904-92-3 1369768-29-5 1547707-34-5

MSDS等安全信息

GHS符号GHS05,GHS06,GHS09
危险类别急性毒性类别3(经皮)
急性毒性类别4(经口)
皮肤腐蚀类别1B
严重眼损伤类别1
水生慢性毒性类别2
Aquatic Acute 2
警示词Danger
危险描述H311 |皮肤接触会中毒.
H302 |吞咽有害.
H314 |造成严重皮肤灼伤和眼损伤.
H318 |造成严重眼损伤.
H411 |对水生生物有毒并具有长期持续影响.
H401 |Toxic to aquatic life
防范说明P260-P264-P270-P273-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P361+P364-P363-P391-P405-P501
危险等级6.1
UN编号2811.0
包装等级Ⅲ

欧盟法规

C&L通报

上下游产品

3-fluorophenylacetonitrile (1S,5R)-2-oxo-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexane (1S,2R)-1-(3-fluorophenyl)-2-(hydroxymethyl)cyclopropane-1-carboxylic acid (1S,2R)-1-(3-fluorophenyl)-2-(hydroxymethyl)cyclopropane-1-carbonitrile {(1S,2R)-[2-(tert-butyldiphenylsilyloxymethyl)-1-(3-fluorophenyl)cyclopropyl]}methanol ((1R,2S)-2-(3-fluorophenyl)-2-((p-tosyloxy)methyl)cyclopropyl)methyl acetate ((1R,2S)-2-(((2,4-dimethylpyrimidin-5-yl)oxy)methyl)-2-(3-fluorophenyl)cyclopropyl)methanol

合成工艺路线路线简述

海关参考信息

2902600000-乙苯
2902700000-异丙基苯
2905121000-正丙醇
2905399002-1,4-丁二醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9828336-B2
优先权日:2012-02-17
标题:Methods and compounds useful in the synthesis of orexin-2 receptor antagonists
发明人：MONIZ GEORGE ANTHONY; WILCOXEN ANNIE ZHU; BENAYOUD FARID; TANAKA TOSHIAKI; SORIMACHI KEIICHI
权利人:EISAI R&D MAN CO LTD
摘要:The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists.

专利号:CN-104114524-B
优先权日:2012-02-17
标题 :Methods and compounds for the synthesis of orexin-2 receptor antagonists

专利号:US-9416109-B2
优先权日:2012-02-17
标题:Methods and compounds useful in the synthesis of orexin-2 receptor antagonists

专利号:US-2016318858-A1
优先权日:2012-02-17
标题 :Methods and compounds useful in the synthesis of orexin-2 receptor antagonists

专利号:US-2015025237-A1
优先权日:2012-02-17
标题 :Methods and Compounds Useful in the Synthesis of Orexin-2 Receptor Antagonists

专利号:EP-2814798-B1
优先权日:2012-02-17
标题:Methods and compounds useful in the synthesis of orexin-2 receptor antagonists