CAS: 104-40-5; 4-Nonylphenol

该化合物是属于亚烷酚类的有机化合物,其特点是附于一个酚环的无基组,一般是一种无色的,具有独特气味的黄黄色粘液,因其表面活性特性而闻名,在包括洗涤剂,乳化剂和塑料添加剂在内的各种工业应用中有用. 4-Nylphenol是疏水化合物,它能够与油和脂肪相互作用,提高清洁产品的效率.然而,它也因其环境持久性和潜在的内分泌干扰效应而得到承认,引起人们对其对水生生物和人类健康的影响的关切.由于这些关切,该化合物的使用在许多区域受到管制.该化合物在有机溶剂中是可溶的,但水溶解性有限,这助长了其在水生生物中的生物累积潜力.

结构式图片

欧盟法规

《欧盟PIC法规》欧盟《植物保护产品法规》REACH注册ECHA物质ECHA物质OtherC&L通报欧盟《水框架指令》附件XREACH预注册欧盟候选物质清单

上下游产品

CAS号14392-69-9 4'-羟基苯壬酮 | CAS号32604-44-7 Phenol,4-nonyl-... | CAS号4397-53-9 4-苄氧基苯甲醛 | CAS号111-83-1 1-溴代正辛烷 | CAS号32588-84-4 1-(4-methoxyphe... | CAS号764-85-2 壬酰氯 | CAS号108-95-2 苯酚 | CAS号103526-64-3 2,6-dibromo-4-n... | CAS号20427-84-3 壬基酚聚氧乙烯醚(4-N-NP2EO) | CAS号103526-64-3 2,6-dibromo-4-n... | CAS号32604-44-7 Phenol,4-nonyl-... | CAS号6178-32-1 4-壬基苯缩水甘油醚 | CAS号1258-75-9 2-(2-hydroxy-5-... | CAS号7598-63-2 1,2-Propanediol... | CAS号79494-14-7 5-nonylquinolin-8-ol | CAS号93913-80-5 6-[1-(hydroxyam... | CAS号59986-54-8 6-[(hydroxyamin... | CAS号62529-25-3 2-nitro-4-nonyl...

合成工艺路线路线简述

  • 合成目标产物 4-Nonylphenol 主要起始原料 Nonanoyl Chloride
  • (文献来源)合成步骤主要原料 Nonanoyl Chloride
📜4-壬基苯基乙酸酯置于aluminum (III) Chloride,盐酸体系中,用 甲苯,水 用作溶剂,化学反应 11.0H,反应生成对壬基酚
参考文献: Process For The Purification Of Hydroxyaryl-Aldhydes And Ketones And Their Use In The Production Of Hydroxyaryl Oxime Derivatives[fr] Processus De Purification D'Hydroxyaryl Aldehydes Et Cetones Et Leur Utilisation Dans La Production De Derives D'Hydroxyaryl Oxime
标题: Process For The Purification Of Hydroxyaryl-Aldhydes And Ketones And Their Use In The Production Of Hydroxyaryl Oxime Derivatives[fr] Processus De Purification D'Hydroxyaryl Aldehydes Et Cetones Et Leur Utilisation Dans La Production De Derives D'Hydroxyaryl Oxime
摘要:一种用于纯化羟基芳基醛和酮的过程,包括以下步骤:1)向包含羟基芳基醛或羟基芳基酮的第一组分中加入矿酸;2)用水洗涤步骤1中得到的混合物;3)从步骤2中分离出包含羟基芳基醛或羟基芳基酮的第二个组分.

海关参考信息

专利信息


专利号:US-2025101045-A1
优先权日:2022-01-18
标题:Synthesis of boron-containing amidoxime reagents and their application to synthesize functionalized oxadiazole and quinazolinone derivatives
发明人:DAS BHASKAR
权利人:LONG ISLAND UNIV
摘要:The present disclosure is concerned with borylated amidoximes useful in the synthesis of biologically relevant drug-like molecules, including functionalized oxadizole and quinazolinone derivatives. Also disclosed are methods of making borylated amidoximes, methods of making functionalized oxadiazole and quinazolinone compounds using the amidoximes, and functionalized oxadiazole and quinazolinone compounds prepared from borylated amidoximes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-4084060-A
优先权日:1976-11-18
标 题:Process for the synthesis of hydroxyethyl cellulose with improved resistance to enzyme catalyzed hydrolysis
发明人:GLASS JR JOSEPH EDWARD; LOWTHER ROY GALE
权利人:UNION CARBIDE CORP
摘要:A process for the synthesis of hydroxyethyl cellulose having improved resistance of enzyme catalyzed hydrolysis is provided by employment of a controlled, optimum amount of available water for swelling the cellulose in aqueous caustic reaction medium in hydroxy ethoxylation sequences of first high and then low ratios of caustic:cellulose.

专利号:US-2003130433-A1
优先权日:2001-10-30
标题 :Process for the production of graft polymers
发明人:WENZ ECKHARD; BUCHHOLZ VERA; EICHENAUER HERBERT; WOLF UDO; BORN RALF-JURGEN; JANSEN ULRICH; DIETZ WOLFGANG
摘要:A process of preparing a graft polymer (e.g., an ABS graft copolymer), which involves determining the concentration of at least one reaction component during the course of the reaction by means of Raman spectroscopy, is disclosed. The process, more particularly, comprises: (a) synthesizing the graft polymer from a reaction mixture comprising reactive components (e.g., monomers such as styrene and acrylonitrile, and a graft base); (b) analyzing the reaction mixture, at intervals, during the synthesis of the graft polymer, by means of Raman spectra; (c) recording the results of the Raman spectra analysis; (d) determining the concentration of at least one of said reactive components (e.g., styrene) by means of spectral evaluation of the recorded Raman spectra; and (e) terminating the synthesis reaction of the graft polymer when the concentration of at least one of the reactive components has reached a predetermined concentration value.

专利号:US-5300703-A
优先权日:1993-04-05
标 题:Alkylphenol synthesis using heteropoly acid catalysts
发明人:KNIFTON JOHN F
权利人:TEXACO CHEMICAL
摘要:Disclosed is a one step method for synthesis of alkylphenols which comprises reacting phenol with the corresponding olefin under adiabatic conditions in the presence of a catalyst comprising a heteropoly acid represented by the structure: H8-n(XM12O40) where x=P or Si, M=Mo or wv and n is an integer which is 4 or 5, alone, or deposited on an inert support, at a temperature of from 60 degrees C. to 250 degrees C. and a pressure of from near atmospheric to about 500 psi.

专利号:US-5171896-A
优先权日:1992-03-05
标 题 :Alkylphenol synthesis using acid-modified inorganic clay catalysts
发明人:KNIFTON JOHN F; SHEU YU-HWA E
权利人:TEXACO CHEMICAL
摘要:Disclosed is a one step method for synthesis of alkylphenols which comprises reacting phenol with the corresponding olefin under adiabatic conditions in the presence of a catalyst comprising an acidic montmorillonite clay having the structure: Mx/nn+xyH2O(Al4-xMgx)(Si8)O20(OH)4 where M represent the interlamellar (balancing cation, normally sodium or lithium) and x, y and n are integers, wherein the acidic clay has been pretreated with an acid and optionally has deposited thereon an acid selected from the group consisting hydrogen fluoride, a fluorosulfonic acid or a mineral acid, at a temperature of from 60 DEG C. to 250 DEG C. and a pressure of from near atmospheric to about 500 psi.

专利号:US-2024309142-A1
优先权日:2023-03-17
标题 :Capped block copolymers, their synthesis, manufacture, and methods of use
发明人:MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON
权利人:ECOLAB USA INC
摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.

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品牌试剂参考报价(招募中)

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✅ COA系统入驻 | 共享模式

主要参考文献


1: Fan X, Kubwabo C, Wu F, Rasmussen PE. Analysis of Bisphenol A, Alkylphenols, and Alkylphenol Ethoxylates in NIST SRM 2585 and Indoor House Dust by Gas Chromatography-Tandem Mass Spectrometry (GC/MS/MS). J AOAC Int. 2018 Jun 26. doi: 10.5740/jaoacint.18-0071. [Epub ahead of print] doi: 10.1016/j.foodchem.2018.03.074. Epub 2018 Mar 19. doi: 10.1016/j.ecoenv.2018.02.039. Epub 2018 Feb 22. doi: 10.1016/j.watres.2018.02.014. Epub 2018 Feb 10. doi: 10.1016/j.chemosphere.2017.12.093. Epub 2017 Dec 19. doi: 10.1016/j.chemosphere.2017.08.105. Epub 2017 Aug 22. doi: 10.1016/j.chemosphere.2017.06.083. Epub 2017 Jun 21. doi: 10.1016/j.bios.2017.05.026. Epub 2017 May 18. doi: 10.1016/j.nbt.2017.05.004. Epub 2017 May 11. doi: 10.1016/j.watres.2016.07.027. Epub 2016 Jul 15. doi: 10.1002/chem.201601329. Epub 2016 Jul 8. doi: 10.1016/j.ygcen.2016.07.002. Epub 2016 Jul 5. doi: 10.1016/j.chroma.2016.06.004. Epub 2016 Jun 4. doi: 10.1007/s11356-016-6656-7. Epub 2016 Apr 20. doi: 10.1016/j.jes.2015.08.006. Epub 2015 Oct 1. doi: 10.1016/j.marpolbul.2016.03.003. Epub 2016 Mar 19. doi: 10.1016/j.jhazmat.2016.01.075. Epub 2016 Feb 1. doi: 10.1002/etc.3334. Epub 2016 May 10. doi: 10.1016/j.talanta.2015.11.008. Epub 2015 Nov 4.

合成参考文献


参考文献:10.1002/elps.200900515
摘要:Wu W, Yuan X, Wu X, Lin X, Xie Z. Analysis of phenolic xenoestrogens by pressurized CEC with amperometric detection. Electrophoresis. 2010 Mar;31(6):1011–8. doi: 10.1002/elps.200900515.
参考文献:10.1016/j.chemosphere.2010.01.041
摘要:Lashermes G, Houot S, Barriuso E. Sorption and mineralization of organic pollutants during different stages of composting. Chemosphere. 2010 Apr;79(4):455–62. doi: 10.1016/j.chemosphere.2010.01.041.
参考文献:10.1016/j.aquatox.2011.06.011
摘要:Vicquelin L, Leray-Forget J, Peluhet L, LeMenach K, Deflandre B, Anschutz P, Etcheber H, Morin B, Budzinski H, Cachot J. A new spiked sediment assay using embryos of the Japanese medaka specifically designed for a reliable toxicity assessment of hydrophobic chemicals. Aquat Toxicol. 2011 Oct;105(3-4):235–45. doi: 10.1016/j.aquatox.2011.06.011.
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