CAS: 1005-51-2; Tricyclo[3.3.2.02,8]Deca-3,6,9-Triene

该化合物是一个多环碳氢化合物,其特点是其独特的三环结构,由三个相互关联的环丙烷和环丁烷环组成,该化合物具有一个共生的双环环环,有助于其稳定性和反应性.多种双环碳化合物的存在,可以产生潜在的电子生殖反应,使其成为有机合成和材料科学的一个主题.三环[3.3.2.0]Decaa-3,6,9-trien在室内温度下一般是无色的,在浅黄色液体,与较大的碳氢氢化合物相比,其沸点相对较低.分子结构具有有趣的光学和电子特性,使它成为有机电子和光学应用的候选物.此外,由于其碳原子的独特安排,它可能表现出紧张,影响其化学行为和再活动.总体而言,该复合物是研究多环芳烃特性和反应的宝贵模型.

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      专利信息


      专利号:US-12358952-B2
      优先权日:2021-01-19
      标 题 :Compositions and methods of synthesizing shape shifting cyclic peptides (Sscp) and their use in the identification of novel therapeutic compounds
      发明人：STOWELL MICHAEL; OLD WILLIAM; WORRELL BRADY; MAYER JOHN
      权利人:UNIV COLORADO REGENTS
      摘要:The invention described herein includes a novel platform for the development of novel shapeshifting drug-like compounds that overcome physical mass limitations as they possess the ability to interconvert internally and spontaneously, i.e., shapeshift, between multiple chemical structures with varying pharmacophore properties. In one preferred embodiment, the invention include systems, methods, and compositions for the synthesis of novel bullvalene amino acid (Bvas) compounds that may further be incorporated into Shape Shifting Cyclic Peptides (SSCP) with varying pharmacophore properties and their use as novel therapeutic compounds.

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      摘要:Taylor, R. E.; Diène, C. R.; Daly, E. M., Science of Synthesis, (2009) 46, 559.
      摘要:de Meijere, A.; Kozhushkov, S. I., Science of Synthesis, (2009) 48, 509.
      摘要:de Meijere, A.; Kozhushkov, S. I., Science of Synthesis, (2009) 48, 516.
      摘要:Saikawa, Y.; Nakata, M., Science of Synthesis Knowledge Updates, (2018) 3, 389.
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