CAS: 618-31-5; (Dibromomethyl)Benzene

该化合物是属于溴化芳烃类的有机化合物,其特征是甲状腺基质,其两个溴原子相对于甲基组群而言被替换为甲状腺位置的两种溴原子.该化合物一般是无色的,可粉黄的,具有典型的芳香味.该化合物在有机溶剂中具有中度溶解性,但由于其疏水性,溶解于水中.阿尔法,阿尔法-二溴氯乙烯主要用于有机合成,并用作各种化合物生产中的中间体.其溴基质的二溴基质增强了其再活动性,使其在电动替代反应中有用.然而,重要的是要谨慎地处理该物质,因为它可能构成健康风险,包括潜在的毒性和环境危害.适当的安全措施,包括使用个人防护设备和适当的通风,在与该化合物合作时至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

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CAS号3112-90-1 苄基甲基砜 | CAS号58751-73-8 [Bis(methylsulf... | CAS号103-82-2 苯乙酸 | CAS号4118-36-9 6,7-二甲氧基-1-苯基-1... | CAS号4360-47-8 3-苯基丙烯腈 | CAS号93-54-9 1-苯基-1-丙醇 | CAS号883-93-2 2-苯基苯并噻唑 | CAS号833-50-1 2-苯基苯并恶唑 | CAS号716-79-0 2-苯基苯并咪唑 | CAS号3162-96-7 甲基-4,6-O-亚苄基-Α-...

合成工艺路线路线简述

    📜二氯甲基苯置于三溴化硼体系中,化学反应生成 α,α-二溴甲苯
    参考文献:Kondratenko,N.V. Et Al.,Journal Of Organic Chemistry Ussr (English Translation),1970,Vol. 6,P. 1436-1439
    标题:Kondratenko,N.V. Et Al.,Journal Of Organic Chemistry Ussr (English Translation),1970,Vol. 6,P. 1436-1439

    海关参考信息

    专利信息


    专利号:US-6133409-A
    优先权日:1996-12-19
    标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
    发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
    权利人:AVENTIS PHARM PROD INC
    摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

    专利号:US-7138554-B2
    优先权日:2001-06-14
    标题 :Synthesis of (dibromocyclobuta) aromatic compounds
    发明人:STANGER AMNON
    权利人:TECHNION RES & DEV FOUNDATION
    摘要:A method for the synthesis of cyclobuta aromatic compounds by cyclizing two ortho dibromoalkyl substituents is described. Using a mediator, such as nickel metal, and continuous removal of product from contact with the mediator, high product yields are achieved. A method for bromination of ortho alkyl substituents of aromatic compounds is also described.

    专利号:EP-0946478-B1
    优先权日:1996-12-19
    标题 :Process for the solid phase synthesis of aldehydes, ketones and hydroxamic acid compounds
    发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
    权利人:AVENTIS PHARMA INC
    摘要:This invention is directed to processes for the solid-phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds and to polymeric hydroxylamine resin compounds useful therefor.

    专利号:US-6710208-B2
    优先权日:1996-12-19
    标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
    发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
    权利人:AVENTIS PHARMA INC
    摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

    专利号:US-8933181-B2
    优先权日:2006-10-06
    标题:Branched polymers and methods for their synthesis and use
    发明人:MOURI HIROSHI; LUO STEVEN; KURASCH JESSICA; ROBERTSON CHRISTOPHER G; WARREN SANDRA
    权利人:MOURI HIROSHI; LUO STEVEN; KURASCH JESSICA; ROBERTSON CHRISTOPHER G; WARREN SANDRA; BRIDGESTONE CORP
    摘要:Branched polymers including multi-branched polymers, functionalized branched polymers, star-branched polymers, and dendigraft polymers. Methods for the synthesis of branched polymers and method for the use of branched polymers in tire components are also included.

    专利号:WO-2008148560-A1
    优先权日:2007-06-07
    标题 :New hybrid compounds of nucleobases and organic redox molecules and their use
    发明人:ASAFTEI SIMONA CARMEN
    权利人:UNIV OSNABRUECK; ASAFTEI SIMONA CARMEN
    摘要:The present invention relates to new compounds as well as methods for the synthesis of the same, said compounds comprise a redox active group, e.g. a 4,4-bipyridine (viologen), a 1,2-di(4-pyridyl)ethane, a 2,7-diazapyrene or 2,9-diazaperylene group and a N-heterocyclic nucleobase (HB), also referred to as base.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:de Meijere, A.; Kozhushkov, S. I., Science of Synthesis, (2009) 48, 540.
    摘要:Irudayanathan, F. M.; Lee, S., Science of Synthesis Knowledge Updates, (2019) 2, 25.
    摘要:Podlech, J., Science of Synthesis Knowledge Updates, (2018) 4, 194.
    摘要:Yoshimatsu, M., Science of Synthesis Knowledge Updates, (2016) 2, 386.
    参考文献:10.1038/s41557-018-0042-7
    摘要:Kale SS, Villequey C, Kong XD, Zorzi A, Deyle K, Heinis C. Cyclization of peptides with two chemical bridges affords large scaffold diversities. Nat Chem. 2018 Jul;10(7):715–23. doi: 10.1038/s41557-018-0042-7.
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