CAS: 54549-26-7; (2R,3S,4S,5R)-2-(Hydroxymethyl)-6-(Tetradecyloxy)Tetrahydro-2H-Pyran-3,4,5-Triol

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      D-葡萄糖 D-Glu 2280-44-6

      合成工艺路线路线简述

        📜D-葡萄糖,十四醇置于对甲苯磺酸体系中,化学反应 8.0H,反应生成 十四烷基 D-葡糖苷
        参考文献:磷酸烷基寡糖苷的制备及其表面活性
        标题:磷酸烷基寡糖苷的制备及其表面活性
        摘要:通过使烷基寡糖苷与氯氧化磷反应来制备磷酸化的烷基寡糖苷表面活性剂系列.烷基寡糖苷是通过常规方法获得的,其中葡萄糖与含有10-18个碳原子的脂肪醇反应.已经发现这些新型的磷酸化表面活性剂表现出非常好的表面张力,起泡和润湿能力.发现临界胶束浓度随着表面活性剂的烃链的长度而增加.报告了每个表面活性剂分子的表面过量浓度和界面面积.这些磷酸盐化的表面活性剂还表现出非常好的性能,以改善在氧化氢漂白体系中棉织物的白度和润湿性,并且还发现它们比常规表面活性剂具有更高的生物降解性.
        DOI:10.1007/s11743-010-1190-Y

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        专利信息


        专利号:EP-1493431-B1
        优先权日:2003-07-03
        标题:Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions
        发明人:WIRTH CORINNA DR; BUCHHOLZ HERWIG DR
        权利人:MERCK PATENT GMBH
        摘要:Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for cosmetic or pharmaceutical treatment of skin and hair. Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for: (a) care, preservation or improvement of the general condition of the skin or hair; (b) prevention and/or inhibition of the aging process for human skin or hair; (c) for promoting healing of wounds; (d) for prevention and/or treatment of skin diseases associated with abnormal keratinization, and (e) for prevention and/or treatment of all malignant or benign growths of the dermis or epidermis. An independent claim is also included for a composition containing (A). ACTIVITY : Dermatological; Vulnerary; Antiseborrheic; Antipsoriatic; Cytostatic; Antiinflammatory; Virucide. MECHANISM OF ACTION : Protein glycosylation inhibitor. In a test, human fibroblasts were cultured in the presence of Vitamin C to stimulate collagen synthesis, then lysed and labeled with tritiated glucose for 15 days, Proteins were removed, extraction and precipitation were carried and the amount of bound glucose measured by liquid scintillation counting. Addition of an aqueous-alcoholic extract of Bauhinia fortificata (0.03 mg/ml), reduced protein glycosylation to 55% of that in a control.

        专利号:EP-2401389-A1
        优先权日:2009-02-25
        标 题 :Synthesis of long-chain alkyl glycosides

        专利号:WO-2010097421-A1
        优先权日:2009-02-25
        标题 :Synthesis of long-chain alkyl glycosides

        专利号:EP-2401389-B1
        优先权日:2009-02-25
        标题:Synthesis of long-chain alkyl glycosides
        发明人:ADLERCREUTZ PATRICK; SVENSSON DAVID; MATHEW SINDHU; NORDBERG KARLSSON EVA MARGARETA
        权利人:ENZA BIOTECH AB

        专利号:ES-2870566-T3
        优先权日:2009-02-25
        标 题:Synthesis of long chain alkylglycosides

        专利号:CN-1062734-A
        优先权日:1991-12-06
        标题 :The direct synthesis technique of alkyl glucoside

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