CAS: 4441-63-8; 4-Cyclohexylbutanoic Acid

该化合物是一种有机化合物,其特性是附于丁酸碱的环状结构,这种化合物通常具有与环状碳酸酸和丙烯酸相关的特性,这种化合物可视温度和纯度,对黄色液体或固态无色,可视其温度和纯度而定;Cyclohexane butanoic酸在乙醇和乙醇等有机溶剂中可溶解,但因其对水的恐惧性环环,其溶解性有限. 氨基酸功能组的存在具有酸性,使其得以参与各种化学反应,包括化化和恐吓.这种化合物可用于合成药品,农用化学品和有机合成的中间体.安全数据表明,与许多有机酸一样,应该谨慎处理,以避免皮肤和眼刺激.总的来说,环丁酸是多种化学领域应用的多用途复合体.

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(2-cyclohexyl-ethyl)-malonic acid 6-cyclohex-1-enyl-hexanoic acid cyclohexanone 4-Phenylbutyric acid 4-cyclohexylbutan-1-ol ethyl 4-cyclohexylbutanoate 4-cyclohexyl-1-(1-hydroxy-[2]naphthyl)-butan-1-one 4-cyclohexyl-1-(2-hydroxy-3,4-dimethyl-phenyl)-butan-1-one

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于乙醇,铂体系中,化学反应生成 环已烷丁酸
    参考文献:The Synthesis Of Some Cycloalkenyl-Substituted Butyro-And Valerolactones1
    标题:The Synthesis Of Some Cycloalkenyl-Substituted Butyro-And Valerolactones1
    摘要:
    DOI:10.1021/ja01165A099

    海关参考信息

    专利信息


    专利号:US-4256646-A
    优先权日:1978-06-29
    标题:Synthesis of optically pure thromboxanes
    发明人:HERNANDEZ OSCAR; BEND JOHN R; ELING THOMAS E; MCKINNEY JAMES D
    权利人:US HEALTH EDUCATION & WELFARE
    摘要:In an elegant stepwise process for the production of intermediates of thromboxanes such as TXB 2 from a chiral glucose starting material such as α-methylglucoside, those steps comprising: ##STR1## A key modification introduced in this synthetic sequence is the use of 4-dimethylaminopyridine for the selective alkylation of primary alcohols in the presence of unprotected secondary alcohols and for the controlled acylation of methylglucoside. The former application has large potential use in the synthesis of nucleosides, polynucleotides, and carbohydrate derivatives.

    专利号:US-6664282-B2
    优先权日:1999-09-17
    标 题:Synthesis of [3,5,7]-1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds
    发明人:ELABDELLAOUI HASSAN M; OSTRESH JOHN M; HOUGHTEN RICHARD A
    权利人:TORREY PINES INST
    摘要:Individual substituted [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-one compounds and their pharmaceutically-acceptable salts are disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.

    专利号:US-5856107-A
    优先权日:1997-02-04
    标 题 :Combinatorial libraries of imidazol-pyrido-indole and imidazol-pyrido-benzothiophene derivatives, methods of making the libraries and compounds therein
    发明人:OSTRESH JOHN M; HOUGHTEN RICHARD A
    权利人:TREGA BIOSCIENCES INC
    摘要:The invention provides a rapid approach for combinatorial synthesis and screening of libraries of imidazol-pyrido-indole and imidazol-pyrido-benzothiophene compounds. The present invention further provides methods of preparing the libraries and the individual compounds made by the combinatorial synthesis.

    专利号:US-7390801-B2
    优先权日:1996-12-23
    标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:THORSETT EUGENE D; PLEISS MICHAEL A; LATIMER LEE H; JOHN VARGHESE; FREEDMAN STEPHEN; BRITTON THOMAS C; AUDIA JAMES A; REEL JON K; DRESSMAN BRUCE A; DROSTE JAMES J; HENRY STEVEN S; STUCKY RUSSELL D; PORTER WARREN J
    权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:WO-9834113-A1
    优先权日:1997-02-04
    标题 :Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
    发明人:OSTRESH JOHN M; MEYER JEAN-PHILIPPE; DOOLEY COLETTE T; HOUGHTEN RICHARD A; BLONDELLE SYLVIE E; SCHONER CHRISTA C
    权利人:TREGA BIOSCIENCES INC
    摘要:The invention provides a rapid approach for combinatorial synthesis and screening of combinatorial libraries of bicyclic guanidine compounds. The present invention further provides the compounds made by the combinatorial synthesis and individually as well as methods of using the same.

    专利号:US-6359144-B1
    优先权日:1997-02-04
    标 题 :Combinatorial libraries of bicyclic guanidine derivatives and compounds therein
    发明人:OSTRESH JOHN M; MEYER JEAN-PHILIPPE; DOOLEY COLETTE T; BLONDELLE SYLVIE E; SCHONER CHRISTA C; HOUGHTEN RICHARD A
    权利人:LION BIOSCIENCE AG
    摘要:The invention provides a rapid approach for combinatorial synthesis and screening of combinatorial libraries of bicyclic guanidine compounds. The present invention further provides the compounds made by the combinatorial synthesis and individually as well as methods of using the same.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: D Y Kim, Et Al. Biosynthesis Of Polyhydroxyalkanoate Copolyester Containing Cyclohexyl Groups By Pseudomonas Oleovorans. Int J Biol Macromol. 2001 Oct 22;29(3):145-50.
    [参考文献]: H J Ougham, Et Al. Metabolism Of Cyclohexaneacetic Acid And Cyclohexanebutyric Acid By Arthrobacter Sp. Strain Ca1. J Bacteriol. 1982 Jun;150(3):1172-82.

    合成参考文献


    参考文献:10.1016/j.chemosphere.2019.06.110
    摘要:Yu X, Lee K, Ulrich AC. Model naphthenic acids removal by microalgae and Base Mine Lake cap water microbial inoculum. Chemosphere. 2019 Nov;234():796–805. doi: 10.1016/j.chemosphere.2019.06.110.
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