专利号:US-9896523-B2 优先权日:2015-06-26 标题 :Ziegler-Natta catalyst synthesis and process thereof 发明人:SINGH GURMEET; KUMAR NARESH; KAUR SUKHDEEP; BANTU BHASKER; KAPUR GURPREET SINGH; SHASHIKANT 权利人:INDIAN OIL CORP LTD 摘要:The present invention describes a process of preparing a catalyst for olefin polymerization comprising: (i) treating a magnesium metal with an organohalide along with an internal donor to obtain a reaction mixture having solid component (A); (ii) treating the reaction mixture having solid component (A) with an acyl halide to obtain a reaction mixture having solid component (B); and (iii) treating the reaction mixture having solid component (B) of step (ii) with a transition metal compound to obtain the catalyst. The present invention also relates to a process for preparation of a catalyst system from said catalyst and preparation of a polyolefins from the catalyst system.
专利号:CN-102557851-A 优先权日:2011-12-13 标 题:A new method for the synthesis of tapentadol hydrochloride and its analogues
专利号:US-10270034-B2 优先权日:2014-05-26 标题 :Tetra-aryl indacenodithiophene-based polycyclic polymers and their use 发明人:MITCHELL WILLIAM; D'LAVARI MANSOOR; WANG CHANGSHENG; SPARROWE DAVID 权利人:MERCK PATENT GMBH 摘要:The present invention relates to compounds comprising a tetra-aryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.
专利号:US-4261974-A 优先权日:1979-11-13 标题:Valproic acid immunogen conjugates and antibodies thereto 发明人:BUCKLER ROBERT T; BURD JOHN F; WONG RAPHAEL C 权利人:MILES LAB 摘要:Reagents for use in binding assays, particularly immunoassays, to determine valproic acid in liquid media such as serum. Such reagents include antibody to valproic acid and β-galactosyl-umbelliferone-valproic acid conjugates. Also provided are compounds used to prepare such reagents, including valproic acid immunogen conjugates and intermediates in the synthesis of such immunogen conjugates and β-galactosyl-umbelliferone-labeled conjugates.
专利号:US-4292425-A 优先权日:1979-11-13 标题 :βGalactosyl-umbelliferone valproic acid conjugates 发明人:BUCKLER ROBERT T; BURD JOHN F; WONG RAPHAEL C 权利人:MILES LAB 摘要:Reagents for use in binding assays, particularly immunoassays, to determine valproic acid in liquid media such as serum. Such reagents include antibody to valproic acid and β-galactosyl-umbelliferone-valproic acid conjugates. Also provided are compounds used to prepare such reagents, including valproic acid immunogen conjugates and intermediates in the synthesis of such immunogen conjugates and β-galactosyl-umbelliferone-labeled conjugates.
专利号:WO-2014178433-A1 优先权日:2013-05-02 标 题 :METHOD FOR PRODUCING α-SUBSTITUTED CYSTEINE OR SALT THEREOF OR INTERMEDIATE FOR SYNTHESIS OF α-SUBSTITUTED CYSTEINE
[参考文献]: Brian C Evans, Et Al. Endosomolytic Nano-Polyplex Platform Technology For Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction. Acs Nano. 2015 Jun 23;9(6):5893-907. [参考文献]: Xi Zhan, Et Al. Controlled Endolysosomal Release Of Agents By Ph-Responsive Polymer Blend Particles. Pharm Res. 2015 Jul;32(7):2280-91.