CAS: 21499-23-0; (R)-8-Hydroxy-3-(3-Hydroxy-4-Methoxyphenyl)Isochroman-1-One

上下游产品

-3,4-dihydro-3-(3-hydroxy-4-methoxyphenyl)-1H-2-benzopyran-1-one(3R)-(+)-8-(1R,4S)-camphanoyloxy-3,4-dihydro-3-(3-hydroxy-4-methoxyphenyl)-1H-2-benzopyran-1-one (R)-8-hydroxy-3-(4-methoxy-3-(methoxymethoxy)phenyl)-3,4-dihydrois°Coumarin (1R)-2-{2-[(S)-4-isopropyl-4,5-dihydrooxazol-2-yl]-3-methoxyphenyl}-1-(4-methoxy-3-(methoxymethoxy)phenyl)ethanol (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)-4,5-dihydrooxazole Thunberginol G Thunberginol A 3'-Hydroxyhydrangeaic acid 3-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-8-(tert-butyl-dimethyl-silanyloxy)-is°Chromen-1-one

📜(3-Acetyloxy-2-Ethoxycarbonylbenzyl)-Triphenylphosphonium Bromide置于palladium On Activated Charcoal 吡啶,氢氧化钾,氢气,Sodium Ethanolate,三氟乙酸体系中,用 乙醇,二氯甲烷,乙酸乙酯 用作溶剂,化学反应 29.88H,反应生成白花前胡甲素
参考文献:Enantiodifferentiation In Taste Perception Of The Phyllodulcins
标题:Enantiodifferentiation In Taste Perception Of The Phyllodulcins
摘要:Both Enantiomers Of Phyllodulcin 1 Have Been Prepared. Ester 2 Was Synthesized In A Wittig Reaction From O-Benzyl Isovanillin. The Corresponding Stilbene Carboxylic Acid 3 Could Be Cyclized With Cf3Co2H To Produce The 3'-Benzyl Ether 4 Of (+/-)-Phyllodulcin. Acylation With (1R,4S)-Camphanoyl Chloride Gave First 5 And After Hydrogenolysis Of The Benzyl Ether Group In 5 The Diastereomeric Esters 6. The Diastereomerically Pure 8-(1R,4S)-Camphanoate (+)-6 Of (R)-Phyllodulcin Could Be Isolated By Repeated Recrystallization. With (1S,4R)-Camphanoyl Chloride The Enantiomeric 8-(1S,4R)-Camphanoate (-)-6 Of O-Phyllodulcin Could Be Prepared Via Ent-5 From A Mixture Of The Diastereomeric Esters Ent-6. Ethanolysis Of (+)-6 Gave (R)-Phyllodulcin [(+)-1] With 99% Ee. The Enantiomeric (S)-(-)-1 With 98% Ee Could Be Obtained From (-)-6. While (+)-1,The Enantiomer occuring In Fermented Leaves Of Amacha,Has An Intense Sweet Taste,The Enantiomer (-)-1 Is Completely Tasteless.
Doi:10.1016/0957-4166(95)00367-X

专利信息

专利号:US-12285423-B2
优先权日:2017-06-28
标题 :Composition for enhancing mitochondrial function
发明人：ANDREEVA LARISA; POMYTKIN IGOR ANATOLIEVICH; SKLADTCHIKOVA GALINA NONINA
权利人:MITOCHOLINE LTD
摘要:A method and composition for enhancing synthesis of adenosine triphosphate (ATP) in mitochondria of brain cells of a human includes providing the composition including a synergistic compound of choline cation and succinate anion (2-) in a molar ratio of choline:succinate of 2:1 in the form of dicholine succinate (DiSu) in a daily dosage that synergistically increases ATP levels in brain cells. The method and composition are formulated to affect frequency and/or severity of various conditions by regulating ATP levels in brain cells. The method and composition are formulated to reduce rate of decline in the brain under conditions of cerebral hypoxia, e.g., due to aging, injury, illness, and the similar conditions.

专利号:BR-112017006139-B1
优先权日:2014-10-03
标题 :Method for the synthesis of rebaudioside m or rebaudioside m and rebaudioside m