专利号:US-9701601-B2 优先权日:2012-06-12 标 题 :Optically active axially chiral alpha-allenic alcohol, synthesis method and use thereof 发明人:MA SHENGMING; YE JUNTAO 权利人:SHANGHAI INST ORGANIC CHEMISTRY CAS 摘要:The present invention relates to an optically active axially chiral α-allenic alcohol, a synthesis method and use thereof. The invention relates to a method of preparing a highly optically active chiral α-allenic alcohol by using propargyl alcohol, aldehyde and chiral α,α-diphenyl-L-prolinol under the protection of tert-butyldimethylsilyl with an accelerant zinc bromide. The axially chiral α-allenic alcohol has the structural formula (I). The method of the present invention has the following advantages: the synthesis route is short, operations are simple, raw materials are readily available, separation and purification are convenient, the substrate has high universality, the total yield is high, and enantioselectivity and diastereoselectivity are high. The highly optically active axially chiral α-allenic alcohol synthesized by the method of the present invention can conveniently synthesize 2,5-dihydrofuran compounds having central chirality and complete chirality, and at the same time can further synthesize axially chiral allenic amine and allenic malonic ester compounds having complete chirality.
专利号:US-5763718-A 优先权日:1994-09-28 标 题 :Process for producing octadienes 发明人:TSUDA TOMOYASU; YOSHIMURA NORIAKI 权利人:KURARAY CO 摘要:A process for producing octadienes comprises, on synthesis of octadienes by reacting butadiene with formic acid in the presence of a palladium catalyst, controlling the reaction pressure at not more than the vapor pressure of butadiene at the reaction temperature employed, thereby suppressing formation of byproducts which would accumulate in a catalyst-containing layer and minimizing the decrease of reaction rate and selectivity which would occur by such accumulation.
专利号:US-8865624-B2 优先权日:2010-09-01 标题 :Inhibitor for tobacco axillary bud growth and method for inhibiting tobacco axillary bud growth 发明人:TANAKA MOTOKI; TANAKA KEIJITSU; SHIBUYA TAKESHI; IKUTA EIJI; YOSHINAGA KOTARO; YAMAGUCHI YUKI 权利人:TANAKA MOTOKI; TANAKA KEIJITSU; SHIBUYA TAKESHI; IKUTA EIJI; YOSHINAGA KOTARO; YAMAGUCHI YUKI; SDS BIOTECH CORP 摘要:The present invention relates to an inhibitor for tobacco axillary bud growth, the inhibitor comprising, as an active ingredient, one or more kinds of very-long chain fatty acid synthesis inhibitors such as a chloroacetamide-based herbicide, fentrazamide, cafenstrole or indanofan; an inhibitor for tobacco axillary bud growth, the inhibitor comprising the aforesaid very-long chain fatty acid synthesis inhibitor together with clorthal-dimethyl or an aliphatic alcohol having 6 to 20 carbon atoms; and a method for inhibiting tobacco axillary bud growth which comprises applying the inhibitor for tobacco axillary bud growth. The inhibitor for tobacco axillary bud growth of the present invention shows sustained drug efficacy at a low concentration, induces neither chemical injury nor disease, and can contribute to the improvement in labor productivity.
专利号:CN-102060658-B 优先权日:2010-12-30 标题 :Catalytic synthesis method of unsaturated alcohol
专利号:CN-102060658-A 优先权日:2010-12-30 标题:Catalytic synthesis method of unsaturated alcohol
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