CAS: 1552-96-1; 4-(Dimethylamino)Cinnamic Acid

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CAS号141-82-2 丙二酸 | CAS号100-10-7 对二甲氨基苯甲醛 | CAS号65946-59-0 1,1-双(三甲基甲硅烷基氧基... | CAS号2929-79-5 diethylacetal o... | CAS号74-88-4 碘甲烷 | CAS号1552-97-2 3-(4-(二甲基氨基)苯基)丙烯酸乙酯 | CAS号110-89-4 六氢吡啶 | CAS号91-22-5 喹啉 | CAS号2562-90-5 Benzenamine, 4-... | CAS号112289-77-7 2,3,4,6-tetra-O... | CAS号14125-75-8 1-脱氧-D-葡萄-己-1-烯... | CAS号2592-58-7 PENTA-O-BENZOYL... | CAS号17573-94-3 4-二甲基氨基苯乙炔 | CAS号73718-09-9 3-(4-二甲氨基-苯基)-丙酸 | CAS号85665-76-5 3-(4-(二甲氨基)苯基)丙-1-醇

📜3-[4-(二甲基氨基)苯基]-2-丙烯酸甲酯置于lithium Hydroxide,盐酸体系中,用 水,二乙二醇 用作溶剂,化学反应 0.25H,反应生成4-二甲基氨基肉桂酸
参考文献:Polymer-Assisted Solution-Phase Synthesis Under Combined Ultrasound And Microwave Irradiation: Preparation Of α,β-Unsaturated Esters And Carboxylic Acids,Key Intermediates Of Novel Sigma Ligands
标题:Polymer-Assisted Solution-Phase Synthesis Under Combined Ultrasound And Microwave Irradiation: Preparation Of α,β-Unsaturated Esters And Carboxylic Acids,Key Intermediates Of Novel Sigma Ligands
摘要:The Optimal Conditions To Prepare,-Unsaturated Methyl Esters Via Wittig Reaction Combining Polymer-Assisted Solution-Phase Synthesis (Pasps) Methodology And Simultaneous Ultrasound And Microwave Irradiation Were Established. The Effects Of Temperature,Solvent,And Irradiation Time Were Discussed. Results Clearly Indicated The Superiority Of Combined Ultrasound And Microwave-Assisted Procedure Over Microwave-Assisted Methodology. Moreover,An Efficient Pasps Procedure To Prepare,-Unsaturated Carboxylic Acids Via Tandem Wittig Olefination And Hydrolysis Reaction Was Developed Under Combined Ultrasound And Microwave Irradiation. Generally,A Good Conversion Of Aldehydes To Acids Was Observed. The Optimized Protocols Allowed Us To Quickly Prepare A Small Collection Of Either,-Unsaturated Esters Or Carboxylic Acids,Key Intermediates For The Drug-Discovery Process Of New Sigma Ligands.
Doi:10.1080/00397910902738112

专利信息

专利号:US-2024009104-A1
优先权日:2021-02-09
标 题:Process for extraction and hemi-synthesis of pyranoanthocyanins and skincare cosmetic formulations containing them
发明人：REIS FERNANDES IVA LUZIA; DA SILVA OLIVEIRA PINTO DA SILVA JOANA ALEXANDRA; DA CRUZ BATISTA MATEUS NUNO FILIPE; PEREIRA DE FREITAS VICTOR ARMANDO; COUTO OLIVEIRA HELDER JOSÉ; CARNEIRO ARAUJO PAULA ALEXANDRA; RODRIGUES CORREIA PATRICIA; MARTINS PEREIRA ANA RITA
权利人:UNIV DO PORTO; REQUIMTE REDE DE QUIM E TECNOLOGIA
摘要:A process of extraction of anthocyanins from different foodstuffs or by-products, and their conversion into pyranoanthocyanins compounds, which can be used as pigments having new colors and improved stability to be incorporated into skincare formulations in particular anti-ageing and sun-protection formulations. Cosmetic formulations having the pigments with improved properties of UV protection and moisturizing, anti-dark spots, anti-wrinkles and wound-healing, which can be associated with interesting colors ranging from red to blue depending on the selected pigments in the composition and in the formula composition. The present invention is in the area of organic chemistry, biochemistry, pharmacology and cosmetics for skincare.

专利号:US-9453037-B2
优先权日:2011-07-28
标 题 :Methylphenidate-prodrugs, processes of making and using the same
发明人：GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
权利人:KEMPHARM INC; KEMPHARM INC
摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

专利号:US-9650329-B2
优先权日:2013-06-25
标题:Transition-metal-free N-arylation of tertiary amines using arynes
发明人：BIJU AKKATTU THANKAPPAN; BHOJGUDE SACHIN SURESH; KAICHARLA TRINADH
权利人:COUNCIL SCIENT IND RES; COUNCIL SCIENT IND RES
摘要:The present invention relates to transition-metal-free process for the synthesis of tertiary arylamines comprises coupling reaction between arynes and N,N-dimethyl aniline compounds in presence of 18-crown-6, KF and THF.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:WO-2022172170-A1
优先权日:2021-02-09
标 题 :Process for extraction and hemi-synthesis of pyranoanthocyanins and skincare cosmetic formulations containing them

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.