CAS: 13657-68-6; (3S,10S,E)-3-Isopropyl-6,10-Dimethylcyclodec-6-Ene-1,4-Dione
- 英文名称(3S,10S,E)-3-Isopropyl-6,10-Dimethylcyclodec-6-Ene-1,4-Dione
- 中文名称莪二酮
- IUPAC名称(3S,10S,E)-3-isopropyl-6,10-dimethylcyclodec-6-ene-1,4-dione
- 其它别名Curdione; Germacr-1(10)-Ene-5,8-Dione; (3S,6E,10S)-6,10-Dimethyl-3-Propan-2-Ylcyclodec-6-Ene-1,4-Dione; (+)-Curdione; (3S,6E,10S)-6,10-Dimethyl-3-(Propan-2-yl)Cyclodec-6-Ene-1,4-Dione; Cyclodecene-1,4-Dione, 6,10-Dimethyl-3-(1-Methylethyl)-, (3S-(3R
- CAS编号13657-68-6
- MFCD编号:MFCD01725514
- 分子式:C15H24O2分子量:236.35
- 产品CID: 568518
- 产品分类生物化工 → 提取物
物理性质
- 熔点61.5-62.0 °C
- 沸点347.6±42.0 °C at 760 mmHg
- 闪点130.4±24.9 °C
- 密度0.9±0.1 g/cm3
- PSA:34.14
- LogP:3.12
- 折射率1.458
- 蒸汽压0.0±0.8 mmHg at 25°C
- 溶解性DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL
- 外观形态白色至类白色结晶
- 储存条件-20°C
- 产品应用该化合物用于确定内容,识别和药理实验等.药理学和药医学效果:它对鼠标沙科马37,鼠标宫颈癌U14和鼠标EHRLICH 蚂蚁癌具有明显的抑制作用,可以使癌症细胞交叉细胞细胞细胞坏死.用这种产品治疗的EHRLICH 火山癌可以在小鼠中成功获得主动免疫.它在子宫颈癌症临床治疗中具有良好的治疗效果.
合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:CN-115785040-B
优先权日:2022-11-03
标题 :Chiral synthesis of active natural products curcumene and isogermfurolactone
专利号:CN-115785040-A
优先权日:2022-11-03
标题:Chiral synthesis method of active natural products curzerene and isogermacrofuryl lactone
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Wei C, Li D, Liu Y, Wang W, Qiu T. Curdione Induces Antiproliferation Effect on Human Uterine Leiomyosarcoma via Targeting IDO1. Front Oncol. 2021 Feb 26;11:637024. doi: 10.3389/fonc.2021.637024.
2: Liu P, Miao K, Zhang L, Mou Y, Xu Y, Xiong W, Yu J, Wang Y. Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation. Respir Res. 2020 Feb 19;21(1):58. doi: 10.1186/s12931-020-1300-y. Erratum in: Respir Res. 2023 Apr 17;24(1):114.
3: Wang H, Xie B, Shi S, Zhang R, Liang Q, Liu Z, Cheng Y. Curdione inhibits ferroptosis in isoprenaline-induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway. Phytother Res. 2023 Jul 27. doi: 10.1002/ptr.7964. Epub ahead of print. 51(1):73-89. doi: 10.1142/S0192415X23500052. Epub 2022 Dec 3.
合成参考文献
摘要:Zhongliu Yanjiu Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher,Peop. Rep. China, 1994, -(178), 1994
📝 需求与反馈
尽可能描述清楚需求与问题信息
